Red Sox vs Orioles Prediction 8/27/2025 Today’s MLB Picks

In this article we will formulate a Red Sox vs Orioles prediction for this MLB game on Wednesday, August 27th at Camden Yards in Baltimore, Maryland. Let’s take a look at the prediction for this MLB matchup. 

Boston Red Sox Betting Preview

The Boston Red Sox are 73-60 this year after they won the first two games in this series by scores of 4-3 and 5-0. In their game two win, Boston led 1-0 after the second inning and never looked back in the shutout victory. The Red Sox recorded nine hits in the game and they were led by Hamilton, who went 2-3 with one home run and three RBIs in the win. Boston started Giolito, who allowed four hits and zero earned runs over 8.0 innings for the win, while Wilson closed out the game. 

Prior to this series, the Red Sox won three out of four against the Yankees, but did lose both games against the Orioles before that. Boston has won five of their last six games and they are currently second in the AL East standings. The Boston pitching staff has a 3.69 ERA with a 1.28 WHIP and a .243 opponent batting average, while their offense has scored 662 runs with a .253 batting average and a .324 on base percentage this season. Wilyer Abreu (IL) has led Boston with 22 home runs and 69 RBIs, while Trevor Story has added 21 home runs and 83 RBIs this year. The projected starting pitcher for Boston is Brayan Bello, who is 10-6 with a 3.07 ERA and a 1.22 WHIP over 135.0 innings pitched this year. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 60-72 this season after they lost game two by a score of 5-0 on Tuesday night. Baltimore had some decent pitching in the first seven innings, but their offense never showed up in the loss. The Orioles recorded six hits in the game and they were led by Jackson, who went 2-3 in the defeat. Baltimore started Bradish, who allowed four hits and two earned runs over 6.0 innings for the loss, while Hiraldo allowed three earned runs in relief. 

Prior to this series, the Orioles lost three out of four against the Astros, but did win both games against the Red Sox before that. Baltimore has lost five of their last six games and they are currently last in the AL East standings. The Baltimore pitching staff has a 4.69 ERA with a 1.38 WHIP and a .261 opponent batting average, while their offense has scored 570 runs with a .241 batting average and a .306 on base percentage this season. Jackson Holliday has led Baltimore with 15 home runs and 49 RBIs, while Gunnar Henderson has added 16 home runs and 59 RBIs this year. The projected starting pitcher for Baltimore is Roansy Contreras, who is making his first appearance in the MLB this year. 

Why the Red Sox will beat the Orioles 

• The road team has won eight of the Orioles’ last nine games.
• The Orioles have lost each of their last five night games against American League opponents.
• The Orioles have failed to cover the run line in five of their last six games.
• The road team has covered the run line in five of the last six games between the Red Sox and Orioles.
• The Red Sox have led after 3 innings in six of their last eight games against American League opponents that held a losing record.
• The Orioles have trailed after 5 innings in four of their last five night games against American League opponents that held a winning record.

Total Runs Facts

• Four of the Orioles’ last five night games against AL East opponents have gone UNDER the total runs line.
• Three of the Red Sox’s last four night games against AL East opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Orioles’ last eight Wednesday night games against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in eight of the Red Sox’s last nine games.

Baltimore Orioles Player Prop Facts

• Colton Cowser has hit a home run in three of the Orioles’ last four night games against AL opponents that held a winning record.
• Ryan Noda has recorded at least one hit in each of his last seven appearances against the Red Sox.

Boston Red Sox Player Prop Facts

• Jarren Duran has hit a home run in three of the Red Sox’s last four road games against opponents that held a losing record.
• Jarren Duran has recorded at least one hit in each of the Red Sox’s last 10 Wednesday night games against AL opponents that held a losing record.
• Ceddanne Rafaela has recorded a Double in three of the Red Sox’s last four road games against AL East opponents.

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Red Sox vs Orioles Prediction 

Boston comes into this matchup after a nice shutout victory on Tuesday night, as they continue to stack wins in the race for the playoffs. The Red Sox are 32-35 on the road this year, while the Orioles are 31-35 at home. Baltimore is trying to catch Tampa Bay for fourth in the East and they are starting Contreras, who has been used as a starter and reliever in the minors. Boston is starting Bello, who has allowed two earned runs or fewer in four of his last five starts. Take the Red Sox by at least two runs here.