Red Sox vs Blue Jays Prediction 4/28/2026 Today’s MLB Picks

In this article we will formulate a Red Sox vs Blue Jays prediction for this MLB game on Tuesday, April 28th at the Rogers Centre in Toronto, Ontario. Let’s take a look at the prediction for this MLB matchup. 

Boston Red Sox Betting Preview

The Boston Red Sox are 12-17 this year after they won game one by a score of 5-0 on Monday night. Boston took the lead in the fourth inning and never looked back in the shutout win. The Red Sox recorded nine hits in the game and they were led by Abreu, who went 2-4 with one RBI. Suarez allowed one hit and zero earned runs over 8.0 innings for the win, while Weissert closed the game out. Prior to this series, Boston won two out of three against the Orioles, but lost all three against the Yankees before that. 

This season, Boston has a 4.23 ERA with a 1.30 WHIP and a .244 opponent batting average, while they have scored 122 runs with a .234 batting average and a .314 on base percentage. Wilson Contreras has led the Red Sox with six home runs and 19 RBIs, while Trevor Story has added two home runs and 17 RBIs. The projected starting pitcher for Boston is Payton Tolle, who is 0-0 with a 1.50 ERA and a 0.67 WHIP over 6.0 innings pitched this year. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 12-16 this season after they dropped game one by a score of 5-0 last night. Toronto hardly had any success at the plate in game one and they never had a chance in the lopsided loss. The Blue Jays recorded two hits and they committed one error in the game, while they were led by Varsho, who went 1-1. Cease allowed seven hits and four earned runs over 5.2 innings for the loss, while Lee allowed one earned run in relief. Prior to this series, Toronto won two out of three against the Guardians and two out of three against the Angels. 

This season, Toronto has a 4.47 ERA with a 1.33 WHIP and a .247 opponent batting average, while they have scored 110 runs with a .249 batting average and a .308 on base percentage. Andres Gimenez has led the Blue Jays with three home runs and 16 RBIs, while Jesus Sanchez has added four home runs and 15 RBIs. The projected starting pitcher for Toronto is Trey Yesavage, who is making his first appearance of the season. 

Why the Toronto Blue Jays will win

• The Blue Jays have won nine of their last 10 games at Rogers Centre against American League opponents that held a losing record.
• The Red Sox have lost six of their last seven night games after playing the previous day.
• The Blue Jays have covered the run line in each of their last four games as favorites against AL East opponents following a home loss.
• The Red Sox have failed to cover the run line in five of their last six night games against AL East opponents.
• The Red Sox have trailed after 5 innings in 11 of their last 14 night games against American League opponents.

Why the Boston Red Sox will win

• The Red Sox have won each of their last six Tuesday games as road underdogs against AL East opponents.
• The Blue Jays have lost each of their last six Tuesday night games as favorites against AL East opponents.
• The Blue Jays have failed to cover the run line in each of their last 12 Tuesday night games as favorites against AL East opponents.
• The Red Sox have covered the run line in each of their last six Tuesday games as underdogs against AL East opponents.
• The Blue Jays have trailed after 5 innings in six of their last seven games against American League opponents that held a losing record.

Total Runs Facts

• Six of the Red Sox’s last seven night games against American League opponents have gone UNDER the total runs line.
• Six of the Blue Jays’ last seven night games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Blue Jays’ last 11 games as favorites against American League opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Red Sox’s last five games.

Toronto Blue Jays Player Prop Facts

• Alejandro Kirk has hit at least one home run in each of his last three appearances with the Blue Jays as home favorites against AL East opponents.
• George Springer has recorded at least one hit in each of his last 13 home appearances against AL opponents that held a losing record.

Boston Red Sox Player Prop Facts

• Willson Contreras has hit a home run in two of the Red Sox’s last three road games.
• Masataka Yoshida has recorded at least one hit in each of his last 10 road appearances against AL East opponents.

Red Sox vs Blue Jays Prediction 

Boston was able to start this series with a win and they have won three games in a row. The Red Sox are 7-9 on the road this year, while the Blue Jays are 8-8 at home. Toronto has dropped three of their last five and they have allowed 20 runs in those three losses. The Jays are starting Yesavage, who is making his first appearance of the year, while Tolle allowed three hits and one earned run against the Yankees in his first start. This is another great pitching matchup, but I have to side with Boston, as Yesavage may not be completely ready to go. Take the Red Sox here.

David Racey's Pick: Red Sox ML