Rays vs Blue Jays Prediction 9/26/2025 Today’s MLB Picks

In this article we will formulate a Rays vs Blue Jays prediction for this MLB game on Friday, September 26th at the Rogers Centre in Toronto, Ontario. Let’s take a look at the prediction for this MLB matchup. 

Tampa Bay Rays Betting Preview

The Tampa Bay Rays are 77-82 this year after they lost two out of three against Baltimore by scores of 0-6, 6-2, and 5-6. In their game three loss, Tampa Bay led 5-2 in the sixth inning, but their bullpen fell apart for the loss. The Rays recorded 15 hits and they committed one error in the game, while they were led by Morel, who went 1-5 with two RBIs in the loss. TB started Rasmussen, who allowed two hits and zero earned runs over 2.1 innings, while Kelly picked up the loss in relief. 

Prior to that series, the Rays lost two out of three against the Red Sox and split four games with the Blue Jays. Tampa Bay has lost four of their last six games and they are fourth in the AL East standings. The Tampa Bay pitching staff has a 3.87 ERA with a 1.21 WHIP and a .236 opponent batting average, while the offense has scored 707 runs with a .252 batting average and a .313 on base percentage this season. Junior Caminero has led Tampa Bay with 44 home runs and 109 RBIs, while Brandon Lowe has added 31 home runs and 83 RBIs for the Rays this year. The projected starting pitcher for Tampa Bay is Adrian Houser, who is 8-4 with a 3.18 ERA and a 1.27 WHIP over 119.0 innings pitched this year. 

Toronto Blue Jays Betting Preview

The Toronto Blue Jays are 91-68 this season after they lost two out of three against Boston by scores of 1-4, 1-7, and 6-1. In their game three win, Toronto scored the first six runs in the game and was able to cruise to the victory. The Blue Jays recorded seven hits in the game and they were led by Varsho, who went 2-4 with one home run and four RBIs in the win. Toronto started Varland, who allowed zero hits and zero earned runs over 2.0 innings, while Rodriguez picked up the win in relief. 

Prior to that series, the Blue Jays lost two out of three against the Royals and split four games with the Rays. Toronto has lost six of their last eight games and they are tied for first in the AL East standings. The Toronto pitching staff has a 4.22 ERA with a 1.27 WHIP and a .242 opponent batting average, while their offense has scored 776 runs with a .265 batting average and a .333 on base percentage this season. Vladimir Guerrero Jr. has led Toronto with 23 home runs and 83 RBIs, while George Springer has added 31 home runs and 82 RBIs this year. The projected starting pitcher for Toronto is Shane Bieber, who is 3-2 with a 3.57 ERA and a 0.96 WHIP over 35.1 innings pitched this season. 

Why the Blue Jays will beat the Rays 

The Rays have lost 10 of their last 11 road games against American League opponents that held a winning record.
The Blue Jays have won seven of their last eight home games against AL East opponents following a home win.
The Rays have failed to cover the run line in five of their last six road games against American League opponents after playing the previous day.
The favorites have covered the run line in three of the Blue Jays’ last four games.

Total Runs Facts

Four of the last five games between the Rays and Blue Jays at Rogers Centre have gone OVER the total runs line.
Four of the Rays’ last five games after playing the previous day have gone OVER the total runs line.
The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Rays’ last 10 night games.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Blue Jays’ last four games as favorites against American League opponents.

Toronto Blue Jays Player Prop Facts

George Springer has hit a home run in two of the Blue Jays’ last three games as home favorites against AL East opponents.
Shane Bieber has recorded nine or more strikeouts in six of his last seven appearances against AL East opponents that held a losing record.
Ernie Clement has recorded a Double in each of the Blue Jays’ last three games as favorites against the Rays.
Bo Bichette has recorded at least one hit in each of his last 17 appearances against opponents that held a losing record.
Shane Bieber has recorded a win in five of his last six appearances against AL East opponents that held a losing record.
George Springer ranks 5th amongst qualified players for Slugging Percentage (.551) this season.

Tampa Bay Rays Player Prop Facts

Brandon Lowe has hit a home run in each of the Rays’ last two games as underdogs against AL East opponents.
Adrian Houser has recorded four or more strikeouts in four of his last five road appearances against AL opponents that held a winning record.
Taylor Walls has recorded a Double in each of his last three road appearances against AL East opponents.
Taylor Walls has recorded at least one hit in each of the Rays’ last nine road games against AL East opponents that held a winning record.
Junior Caminero ranks 6th in the league in Home Runs (44) this season.

Matchup/League Facts

The Blue Jays rank 1st in the league for strikeouts against this season (1072).
The Blue Jays rank 2nd in the league for on-base percentage this season (.333).
The Rays rank 27th in the league for walks this season (455).
The Rays are one of only four teams in the league to rank top 10 in both steals and batting average this season.

Rays vs Blue Jays Prediction 

Toronto has struggled over the last two weeks, but they picked up a huge win on Thursday night and continue to battle the Yankees in the East. The Blue Jays are 51-27 at home this season, while the Rays are 36-42 on the road. Tampa Bay is coming off of a series loss to Baltimore and they are starting Houser, who has allowed 3+ earned runs in three of his last four outings. Toronto is starting Bieber, who has allowed two earned runs or fewer in back to back starts. I don’t believe in this Tampa Bay pitching staff right now, so I will take the Jays by at least two runs here.