Pittsburgh Pirates vs Washington Nationals Prediction 9/13/2025 Today’s MLB Picks

In this article, we will formulate a Pirates vs Nationals Prediction for this MLB game on Saturday, September 13th at the Nationals Park the second game of this series, with Nationals having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Washington Nationals Preview

The Washington Nationals have a 61-86 record this season and are sitting on the last place of the NL East. The Nationals have a 30-42 home record and are 75-63 in over/under. They are coming off a 6-5 home victory over the Pirates, that ended their two-game losing streak. Over is 7-2 in their last 9 games and are playing the Mets and the Braves next.

The Nationals have a .245 batting average this season, .308 OBP and .391 Slugging percentage. Washington’s pitching staff has a 5.30 ERA and 1.43 WHIP. James Wood leads the Nationals with 143 hits, while CJ Abrams is the team’s best hitter with a .266 batting average. James Wood adds a team-high 88 RBI and leads the team in home runs, with 27.

Andrew Alvarez (L) is the projected starting pitcher for the Nationals, and he has a 1-0 record, 1.86 ERA and 0.93 WHIP.

Pittsburgh Pirates Preview

The Pittsburgh Pirates have a 64-84 record this season and are sitting on the last place of the NL Central. They have a 22-51 road record, and are 60-83 in over/under. They are coming off a 2-3 road defeat by the Orioles, and have six consecutive losses. Under is 5-1 in their last 6 games are playing the Cubs and the Athletics next.

The Pirates have a .232 batting average this season, .305 OBP and .350 slugging percentage. Pittsburgh’s pitching staff has a 3.89 ERA and 1.23 WHIP. Bryan Reynolds leads the Pirates with 131 hits, and a team-high 71 RBI. He is also the team’s best hitter with a .242 batting average, while Oneil Cruz leads the team in home runs, with 19.

Reliever Bubba Chandler (R) is the projected starting pitcher for the Pirates, and he has a 2-1 record, 7.36 ERA and 1.50 WHIP.

Pittsburgh Pirates @ Washington Nationals Betting Trends: September 13, 2025

• Probable Starting Pitcher: Andrew Alvarez      Record this season: 1-0      ERA: 1.86
• Home Record: 1-0
• Last 5 against Pirates: –

Why the Washington Nationals will win

• The Pirates have lost each of their last seven games.
• The Nationals have won each of their last six home games against National League opponents.
• The Nationals have covered the run line in each of their last six home games against National League opponents.
• The Pirates have failed to cover the run line in each of their last four games against National League opponents.
• The Nationals have led after 3 innings in three of their last four home games.
• The Nationals have led after 5 innings in five of their last six home games against National League opponents.

• Probable Starting Pitcher: Bubba Chandler      Record this season: 2-1      ERA: 7.36
• Road Record: 1-0
• Last 5 against Nationals: –

Why the Pittsburgh Pirates will win

• The Pirates have won each of their last five games as underdogs against NL East opponents.
• The Nationals have lost six of their last eight games as home favorites against NL Central opponents.
• The Pirates have covered the run line in each of their last six games as road underdogs following a loss.
• The Nationals have failed to cover the run line in 10 of their last 12 games as home favorites after playing the previous day.
• The Pirates have led after 3 innings in each of their last five games against NL East opponents.
• The Nationals have trailed after 5 innings in each of their last seven day games at Nationals Park against NL Central opponents.
• The Pirates have won the first inning in six of their last eight road games against National League opponents that held a losing record.

Total Runs Facts

• Each of the Nationals’ last six day games as favorites have gone UNDER the total runs line.
• Each of the Pirates’ last four games against NL East opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Nationals’ last four games as favorites against National League opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Pirates’ last six games as underdogs against NL East opponents.

Washington Nationals Player Prop Facts

• Josh Bell has hit a home run in three of his last four appearances in day games against NL Central teams that held a losing record.
• Josh Bell has recorded at least one Double in each of his last three appearances with the Nationals as favorites against NL Central opponents.
• CJ Abrams has recorded at least one hit in eight of his last nine appearances.

Pittsburgh Pirates Player Prop Facts

• Tommy Pham has hit a home run in each of his last two appearances in day games against NL teams that held a losing record.
• Andrew McCutchen has recorded a Double in four of his last five appearances with his team as an underdog against the Nationals.
• Tommy Pham has recorded at least one hit in each of his last 10 road appearances against NL East opponents that held a losing record.

Matchup/League Facts

• The Nationals rank 29th in the league for ERA this season (5.30).
• The Nationals rank 29th in the league for opponent batting average this season (.267).
• The Pirates rank 30th in the league for runs scored this season (532).
• The Pirates rank 30th in the league for home runs this season (106).

Pirates vs Nationals Prediction

The Pirates are 4-2 in their last 6 meetings against the Nationals, and under is 3-1 in their last 4 meetings. 

In this Pirates vs Nationals Prediction, the Nationals are coming as -125 home favorites. We know very little for both starting pitchers, but Alvarez for the Nationals has only two earned runs in his two starts this season, while on the flip side, Chandler was torched in his only start this season, having given up 9 runs in 2.2 innings pitched. The Nats have a better offense, and are better against righties, while the Pirates are weaker against lefties, so I like the value with the home team in this one. Take the Washington Nationals on the moneyline at home.