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Pittsburgh Pirates vs San Francisco Giants Prediction 07/28/2025 Picks

Jul 8, 2025; Kansas City, Missouri, USA; Pittsburgh Pirates starting pitcher Mitch Keller (23) pitches during the second inning against the Kansas City Royals at Kauffman Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images

Jul 8, 2025; Kansas City, Missouri, USA; Pittsburgh Pirates starting pitcher Mitch Keller (23) pitches during the second inning against the Kansas City Royals at Kauffman Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images

MATCHUP Pittsburgh Pirates San Francisco Giants
Team Records 45-62 54-53
Where Oracle Park, San Francisco, California
When Monday, July 28, 2025
Time 09:45 PM EDT
TV MLBN

In this article, we will formulate a Pirates vs Giants prediction for this MLB game on Monday, July 28, at Oracle Park in San Francisco, California. Let’s take a look at the prediction for this MLB matchup.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates (44-62, 13-37 Away) were swept by the Chicago White Sox, swept the Detroit Tigers, and then defeated the Arizona Diamondbacks. Pittsburgh lost Game 1 to Arizona at home, but then won the next two. In a rubber match on Sunday, the Pirates secured a 6-0 victory. Oneil Cruz and Ke’Bryan Hayes led the offense with two runs apiece, while Paul Skenes got the win after allowing no runs on three hits with nine strikeouts and one walk across 6.0 innings of work.

This year, the Pirates average 3.35 runs per game (25th in the MLB) on a .229/.299/.339 triple-slash. When it comes to pitching, the Pirates’ staff has a 3.75 ERA (9th) and 1.20 WHIP (3rd). Bryan Reynolds leads the Pirates with a .232 batting average, ten home runs, and 51 RBI this season.

The projected starting pitcher for the Pirates is Mitch Keller, who is 4-10 in 21 starts this season, with a 3.53 ERA and 1.16 WHIP in 125.0 innings.

San Francisco Giants Betting Preview

The San Francisco Giants (54-52, 28-23 Home) were swept by the Toronto Blue Jays, beat the Atlanta Braves, and were swept by the New York Mets to start the second half of the season. San Francisco scored only five runs in three games against the Mets, including three in the most recent 5-3 defeat on Sunday. Matt Chapman hit a pair of homers and drove in all three runs for the offense, while Randy Rodriguez took the loss in a bullpen day for the Giants.

This season, the Giants average 4.12 runs per game (23rd in the MLB) on a .233/.311/.375 triple-slash. When it comes to pitching, the Giants’ staff has a 3.63 ERA (6th) and 1.27 WHIP (17th). Wilmer Flores leads the Giants with a .248 batting average, 12 home runs, and 59 RBI this season.

Carson Whisenhunt will take the mound for the Giants on Monday. The 24-year-old left-hander has been called up from the minors and will get his first start in the MLB.

Why the Pirates will beat the Giants

Total Runs Facts

Matchup/League Facts

Pirates vs Giants Prediction

The Giants won seven of the previous ten H2H encounters, including three of the last four. However, I am going with the Pirates in this one because I don’t know anything about Carson Whisenhunt, and he will start for the first time in the majors. Mitch Keller, on the other hand, hasn’t allowed more than three runs in his previous eight starts and has been excellent in July, posting a 2.10 ERA. Keller registered four quality starts in a row, and I am backing him to get another one here. Back the Pirates.

Oliver Zivic's Pick: Pirates ML

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