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Pittsburgh Pirates vs Philadelphia Phillies Prediction 5/16/25 MLB Picks

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Philadelphia Phillies (25-18) vs Pittsburgh Pirates (15-29)

Game Info: Friday, May 16, 2025 at 6:45 pm (Citizens Bank Park)

The Line: Betting Odds: Philadelphia Phillies -230 / Pittsburgh Pirates +190 — Over/Under: 8.5

(Get latest betting odds)

The Pittsburgh Pirates and Philadelphia Phillies meet Friday in MLB action at Citizens Bank Park. Here’s a Pittsburgh Pirates vs Philadelphia Phillies Prediction. This article will include a Pittsburgh Pirates vs Philadelphia Phillies Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 15-29 on the year and play the Reds, Brewers, and Diamondbacks next. The Pittsburgh Pirates are batting .220 on the season, have a .301 OBP, and a .328 slugging percentage. The Pittsburgh Pirates pitching staff has a 4.01 ERA and a 1.26 WHIP. Ke’Bryan Hayes leads the Pittsburgh Pirates with 40 hits and 15 RBI, while Bryan Reynolds and Isiah Kiner-Falefa have combined for 66 hits and 28 RBI. 

Andrew Heaney gets the ball for the Pittsburgh Pirates, and he is 2-3 with a 3.15 ERA and 36 strikeouts this season. Heaney is 0-2 with a 8.64 ERA and 6 strikeouts in his career against the Philadelphia Phillies.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 25-18 on the year and play the Rockies, Athletics, and Braves next. The Philadelphia Phillies are batting .257 on the season, have a .335 OBP, and a .402 slugging percentage. The Philadelphia Phillies pitching staff has a 3.90 ERA and a 1.26 WHIP. Trea Turner leads the Philadelphia Phillies with 50 hits and 14 RBI while Nick Castellanos and Kyle Schwarber have combined for 88 hits and 56 RBI.

Ranger Suarez gets the ball for the Philadelphia Phillies, and he is 1-0 with a 5.91 ERA and 11 strikeouts this season. Suarez is 3-0 with a 1.80 ERA and 31 strikeouts in his career against the Pittsburgh Pirates.

Why the Philadelphia Phillies will win

Why the Pittsburgh Pirates will win

Philadelphia Phillies Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Pittsburgh Pirates vs Philadelphia Phillies Prediction

The Pirates can’t string together wins and haven’t won two straight games since April 22-23. Heaney has also been shaky lately, allowing 17 hits and 10 runs in his last 14.1 innings. The Phillies are not only the better team playing the more consistent ball, but Suarez is coming off seven shutout innings against the Guardians. Suarez has also had success against the Pirates, which includes holding current hitters to a .200 batting average and four strikeouts in 20 at bats. I need to see the Pirates win games in a row before they get my attention. Until then, the Pirates are fade material. Give me the Phillies and the RL for max betting value.

Randy Chambers's Pick: Philadelphia Phillies -1.5

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