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Pittsburgh Pirates vs Los Angeles Dodgers Prediction 4/26/25 MLB Picks

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Los Angeles Dodgers (16-10) vs Pittsburgh Pirates (11-16)

Game Info: Saturday, April 26, 2025 at 9:10 pm (Dodger Stadium)

The Line: Betting Odds: Los Angeles Dodgers -270 / Pittsburgh Pirates +220 — Over/Under: 8.5

(Get latest betting odds)

The Pittsburgh Pirates and Los Angeles Dodgers meet Saturday in MLB action at Dodger Stadium. Here’s a Pittsburgh Pirates vs Los Angeles Dodgers Prediction. This article will include a Pittsburgh Pirates vs Los Angeles Dodgers Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 11-16 on the year and play the Cubs, Padres, and Cardinals next. The Pittsburgh Pirates are batting .222 on the season, have a .303 OBP, and a .336 slugging percentage. The Pittsburgh Pirates’ pitching staff has a 3.72 ERA and a 1.15 WHIP. Bryan Reynolds leads the Pittsburgh Pirates with 27 hits and 13 RBI, while Isiah Kiner-Falefa and Oneil Cruz have combined for 46 hits and 21 RBI. 

Mitch Keller gets the ball for the Pittsburgh Pirates, and he is 1-2 with a 4.18 ERA and 20 strikeouts this season. Keller is 2-3 with a 7.54 ERA and 30 strikeouts in his career against the Los Angeles Dodgers.

Los Angeles Dodgers Betting Preview

The Los Angeles Dodgers are 16-10 on the year and play the Marlins, Braves, and Diamondbacks next. The Los Angeles Dodgers are batting .230 on the season, have a .308 OBP, and a .421 slugging percentage. The Los Angeles Dodgers pitching staff has a 3.85 ERA and a 1.30 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 25 hits and 8 RBI, while Teoscar Hernandez and Tommy Edman have combined for 50 hits and 41 RBI.

Roki Sasaki gets the ball for the Los Angeles Dodgers, and he is 0-1 with a 3.20 ERA and 16 strikeouts this season. This will be Sasaki’s first career game against the Pittsburgh Pirates.

Why the Los Angeles Dodgers will win

Why the Pittsburgh Pirates will win

Los Angeles Dodgers Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Pittsburgh Pirates vs Los Angeles Dodgers Prediction

The Dodgers are obviously the clearly more talented team, and Sasaki looks like he’s the real deal through five games. The Dodgers should be favored. However, the Dodgers have lost three straight games, and the Pirates have won enough games recently to where they’re worth a look in the big underdog role. Sasaki has also walked 16 to go with 16 strikeouts, so he leaves the door open for Also, Keller has been solid in his last three starts, allowing 15 hits and five runs in his last 18.1 innings. This line is crazy steep, and it leads me to take a shot with the Pirates and a chance to make more than two times my money. 

Randy Chambers's Pick: Pittsburgh Pirates +220

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