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Pittsburgh Pirates vs Chicago Cubs Prediction 9/13/2026 Today’s MLB Picks

Sep 1, 2026; Chicago, Illinois, USA;  Chicago Cubs pitcher Matthew Boyd (16) delivers the ball during the first inning against the Milwaukee Brewers at Wrigley Field.  Mandatory Credit: Matt Marton-Imagn Images

Sep 1, 2026; Chicago, Illinois, USA; Chicago Cubs pitcher Matthew Boyd (16) delivers the ball during the first inning against the Milwaukee Brewers at Wrigley Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Pittsburgh Pirates Chicago Cubs
Team Records 74-75 83-66
Spread +1.5 -193 -1.5 158
Moneyline +123 -148
Total Over 6.5 (-110) Under 6.5 (-110)
Where Wrigley Field, Chicago, Illinois
When Sunday, September 13, 2026
Time 02:20 PM EDT
TV MLB.TV
In this article, we will formulate a Pirates vs Cubs Prediction for this MLB matchup on Sunday, September 13th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview


The Chicago Cubs have a 83-66 record this season and are sitting in the 2nd place of the NL Central. They have a 43-31 home record and are coming off a 4-3 home win against the Pirates. They will face the Braves and the Reds next.

The Chicago Cubs have a .252 batting average this season, .340 OBP and .431 Slugging percentage. Chicago’s pitching staff has a 4.19 ERA and 1.27 WHIP. Pete Crow-Armstrong is the team’s best hitter with a .279 batting average, leading the team in RBI with 98, adding a team-high 41 home runs.

Matthew Boyd (L) is the projected starting pitcher for the Cubs, and he has a 8-4 record, 4.03 ERA and 1.22 WHIP.

Pittsburgh Pirates Preview


The Pittsburgh Pirates have a 74-75 record this season and are sitting in the 3rd place of the NL Central. They have a 36-41 away record and are coming off a 3-4 road loss against the Cubs. They will face the Brewers and the Royals next.

The Pittsburgh Pirates have a .253 batting average this season, .330 OBP and .401 Slugging percentage. Pittsburgh’s pitching staff has a 4.18 ERA and 1.30 WHIP. Nick Gonzales is the team’s best hitter with a .305 batting average. Brandon Lowe leads the team in RBI with 83, adding a team-high 29 home runs.

Bubba Chandler (R) is the projected starting pitcher for the Pirates, and he has a 7-9 record, 4.25 ERA and 1.34 WHIP.

Pittsburgh Pirates @ the Chicago Cubs Betting Trends: September 13, 2026


Why the Chicago Cubs will win

Why the Pittsburgh Pirates will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Matchup/League Facts

Pirates vs Cubs Prediction


The Cubs are 6-1 in their last 7 meetings against the Pirates and have won their last three meetings in Chicago.

In this Pirates vs Cubs Prediction, the Cubs are coming as -140 home favorites. This total is way too low even with winds blowing in at 10+ mph. Boyd has been in bad form with 3+ runs in four of his last five starts and has been weaker at home with a 5.40 home ERA, while Chandler has a 4.23 road ERA. Both teams average 9.7 runs per game combined in their last 5 games and the Pirates’ bullpen has a 6.52 ERA in that span. This total is too low, so take the over 6.5 in this one.  

Nikos Lagouretos's Pick: Over 6.5

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