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Pittsburgh Pirates vs Chicago Cubs Prediction 9/11/2026 Today’s MLB Picks

Aug 11, 2026; Washington, District of Columbia, USA; Chicago Cubs starting pitcher Shota Imanaga (18) pitches against the Washington Nationals during the second inning at Nationals Park. Mandatory Credit: Geoff Burke-Imagn Images

Aug 11, 2026; Washington, District of Columbia, USA; Chicago Cubs starting pitcher Shota Imanaga (18) pitches against the Washington Nationals during the second inning at Nationals Park. Mandatory Credit: Geoff Burke-Imagn Images

MATCHUP Pittsburgh Pirates Chicago Cubs
Team Records 74-73 81-66
Where Wrigley Field, Chicago, Illinois
When Friday, September 11, 2026
Time 02:20 PM EDT
TV MLB.TV
In this article, we will formulate a Pirates vs Cubs Prediction for this MLB matchup on Friday, September 11th in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview


The Chicago Cubs have a 81-66 record this season and are sitting in the 2nd place of the NL Central. They have a 41-31 home record and are coming off a 6-8 road loss against the Brewers. They will face the Braves and the Reds next.

The Chicago Cubs have a .251 batting average this season, .339 OBP and .429 Slugging percentage. Chicago’s pitching staff has a 4.22 ERA and 1.27 WHIP. Pete Crow-Armstrong is the team’s best hitter with a .281 batting average, leading the team in RBI with 97, adding a team-high 41 home runs.

Shota Imanaga (L) is the projected starting pitcher for the Cubs, and he has a 9-10 record, 3.91 ERA and 1.12 WHIP.

Pittsburgh Pirates Preview


The Pittsburgh Pirates have a 74-73 record this season and are sitting in the 3rd place of the NL Central. They have a 36-39 away record and are coming off a 2-0 road win against the White Sox. They will face the Brewers and the Royals next.

The Pittsburgh Pirates have a .253 batting average this season, .331 OBP and .403 Slugging percentage. Pittsburgh’s pitching staff has a 4.13 ERA and 1.30 WHIP. Nick Gonzales is the team’s best hitter with a .305 batting average. Brandon Lowe leads the team in RBI with 83, adding a team-high 29 home runs.

Wilber Dotel (R) is the projected starting pitcher for the Pirates, and he has a 1-4 record, 4.41 ERA and 1.32 WHIP.

Pittsburgh Pirates @ the Chicago Cubs Betting Trends: September 11, 2026


Why the Chicago Cubs will win

Why the Pittsburgh Pirates will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Matchup/League Facts

Pirates vs Cubs Prediction


The Cubs are 4-1 in their last 5 meetings against the Pirates but have lost two of their last three meetings in Chicago.

In this Pirates vs Cubs Prediction, the Cubs are coming as -180 home favorites. I like the Cubs in this one with Imanaga on the mound, who might be up and down lately, but he is the better pitching option than the Pirates’ reliever. Pittsburgh has been struggling against lefties lately, with just 2 runs per game in their last 5 against southpaws, while the Cubs’ offense has been in very good form with 5.6 runs per game in their last 10. They are also in a desperate bounce-back spot after losing four straight games on the road, so I will take the Cubs on the moneyline in this one.  

Nikos Lagouretos's Pick: Chicago Cubs ML

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