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Pittsburgh Pirates vs Chicago Cubs Prediction 8/16/2025 Today’s MLB Picks

Aug 15, 2025; Chicago, Illinois, USA; Chicago Cubs shortstop Dansby Swanson (7) lays down a sacrifice bunt against the Pittsburgh Pirates during the seventh inning at Wrigley Field. Mandatory Credit: David Banks-Imagn Images

Aug 15, 2025; Chicago, Illinois, USA; Chicago Cubs shortstop Dansby Swanson (7) lays down a sacrifice bunt against the Pittsburgh Pirates during the seventh inning at Wrigley Field. Mandatory Credit: David Banks-Imagn Images

MATCHUP Pittsburgh Pirates Chicago Cubs
Team Records 52-71 69-53
Where Wrigley Field, Chicago, Illinois
When Saturday, August 16, 2025
Time 02:20 PM EDT
TV FS1

The Pittsburgh Pirates and Chicago Cubs meet Saturday in MLB action at Wrigley Field. Here’s a Pittsburgh Pirates vs Chicago Cubs Prediction. This article will include a Pittsburgh Pirates vs Chicago Cubs Pick.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates are 52-71 on the year and play the Blue Jays, Rockies, and Cardinals next. The Pittsburgh Pirates are batting .232 on the season, have a .303 OBP, and a .346 slugging percentage. The Pittsburgh Pirates pitching staff has a 4.04 ERA and a 1.24 WHIP. Bryan Reynolds leads the Pittsburgh Pirates with 111 hits and 61 RBI, while Isiah Kiner-Falefa and Andrew McCutchen have combined for 187 hits and 74 RBI. 

Mike Burrows gets the ball for the Pittsburgh Pirates, and he is 1-4 with a 4.66 ERA and 69 strikeouts this season. This will be Burrows’ second career game against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 68-53 on the year and play the Brewers, Angels, and Giants next. The Chicago Cubs are batting .251 on the season, have a .320 OBP, and a .433 slugging percentage. The Chicago Cubs pitching staff has a 3.85 ERA and a 1.20 WHIP. Nico Hoerner leads the Chicago Cubs with 130 hits and 47 RBI while Pete Crow-Armstrong and Kyle Tucker have combined for 233 hits and 141 RBI.

Shota Imanaga gets the ball for the Chicago Cubs, and he is 8-5 with a 3.19 ERA and 79 strikeouts this season. Imanaga is 2-0 with a 0.00 ERA and 17 strikeouts in his career against the Pittsburgh Pirates.

Why the Chicago Cubs will win

Why the Pittsburgh Pirates will win

Chicago Cubs Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Pittsburgh Pirates vs Chicago Cubs Prediction

The Pirates have had issues stringing together wins lately, and Burrows has allowed eight hits and 10 runs in his last 9.2 innings. The Cubs can’t afford to keep blowing games like this if they’re going to get where they’re trying to go, and Imanaga has a 3.32 ERA and .201 allowed batting average in 40.2 home innings. Imanaga has also owned the Pirates in two career starts. There are no excuses for the Cubs with their ace on the bump. Give me the Cubs.

Randy Chambers's Pick: Chicago Cubs

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