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Pittsburgh Pirates vs Chicago Cubs Prediction 4/12/2026 Today’s MLB Picks

Mar 31, 2026; Chicago, Illinois, USA; Chicago Cubs pitcher Jameson Taillon (50) and catcher Miguel Amaya (9) celebrate after ending the top of the first inning against the Los Angeles Angels at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

Mar 31, 2026; Chicago, Illinois, USA; Chicago Cubs pitcher Jameson Taillon (50) and catcher Miguel Amaya (9) celebrate after ending the top of the first inning against the Los Angeles Angels at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

MATCHUP Pittsburgh Pirates Chicago Cubs
Team Records 9-5 6-8
Where Wrigley Field, Chicago, Illinois
When Sunday, April 12, 2026
Time 02:20 PM EDT
TV MLB.TV
In this article, we will formulate a Pirates vs Cubs Prediction for this MLB matchup on Sunday, April 12th in the third game of this series. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview


The Chicago Cubs have a 6-8 record this season and are sitting in the fifth place of the NL Central. They have a 3-5 home record and are coming off a 3-4 home loss against the Pirates. Their previous three games were a 2-0 home loss against the Pirates, and a 6-2 and a 9-2 road win against the Rays.

The Cubs have a .219 batting average this season, .315 OBP and .342 Slugging percentage. Chicago’s pitching staff has a 3.24 ERA and 1.12 WHIP. Nico Hoerner is the team’s best hitter with a .308 batting average, also leading the team in RBI with 10. Ian Happ adds a team‑high 4 home runs.

Jameson Taillon (R) is the projected starting pitcher for the Cubs, and he has a 0-1 record, 2.53 ERA and 1.22 WHIP.

Pittsburgh Pirates Preview


The Pittsburgh Pirates have a 9-5 record this season and are sitting in the first place of the NL Central. They have a 5-3 away record and are coming off a 4-3 road win against the Cubs. Their previous three games were a 2-0 road win against the Cubs, and an 8-2 home loss and a 7-1 home win against the Padres.

The Pirates have a .240 batting average this season, .329 OBP and .366 Slugging percentage. Pittsburgh’s pitching staff has a 3.02 ERA and 1.32 WHIP. Oneil Cruz is the team’s best hitter with a .345 batting average, also leading the team in RBI with 12 and adding a team‑high 4 home runs.

Bubba Chandler (R) is the projected starting pitcher for the Pirates, and he has a 0-1 record, 3.12 ERA and 1.73 WHIP.

Pittsburgh Pirates @ the Chicago Cubs Betting Trends: April 12, 2026


Why the Chicago Cubs will win


Why the Pittsburgh Pirates will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Pittsburgh Pirates Player Prop Facts

Matchup/League Facts

Pirates vs Cubs Prediction


The Cubs are 8-3 in their last 11 meetings against the Pirates and are 5-3 in their last 8 meetings in Chicago. 

In this Pirates vs Cubs Prediction, the Cubs are coming as -135 home favorites. The Pirates have won both games in this series but now have to go up against Jameson Taillon who has been very good this season. Both pitchers gave up 3 runs in their previous start and both teams have similar bullpen ERA and runs per game, but the Cubs have been better against right-handed pitching, while the Pirates have been weaker against righties, so I believe that is what it takes for them to bounce back today. Take the Cubs on the moneyline.

Nikos Lagouretos's Pick: Chicago Cubs ML

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