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Philadelphia Phillies vs Los Angeles Dodgers Prediction 9/16/2025 Today’s MLB Picks

Sep 15, 2025; Los Angeles, California, USA; Los Angeles Dodgers center fielder Andy Pages (44) hits a solo home run against the Philadelphia Phillies during the ninth inning at Dodger Stadium. Mandatory Credit: Gary A. Vasquez-Imagn Images

Sep 15, 2025; Los Angeles, California, USA; Los Angeles Dodgers center fielder Andy Pages (44) hits a solo home run against the Philadelphia Phillies during the ninth inning at Dodger Stadium. Mandatory Credit: Gary A. Vasquez-Imagn Images

Philadelphia (90-61) vs Los Angeles (84-66)

September 16, 2025 at 10:10 PM EDT

The Line: Betting Odds: Los Angeles +1.5 — Over/Under: +7.5

(Get latest betting odds)

The Philadelphia Phillies and Los Angeles Dodgers meet Tuesday in MLB action at Dodger Stadium. Here’s a Philadelphia Phillies vs Los Angeles Dodgers Prediction. This article will include a Philadelphia Phillies vs Los Angeles Dodgers Pick.

Philadelphia Phillies Betting Preview


The Philadelphia Phillies are 90-61 on the year and play the Diamondbacks, Marlins, and Twins next. The Philadelphia Phillies are batting .261 on the season, have a .331 OBP, and a .432 slugging percentage. The Philadelphia Phillies pitching staff has a 3.83 ERA and a 1.24 WHIP. Trea Turner leads the Philadelphia Phillies with 179 hits and 69 RBI, while Kyle Schwarber and Nick Castellanos have combined for 268 hits and 194 RBI.

Cristopher Sanchez gets the ball for the Philadelphia Phillies, and he is 13-5 with a 2.57 ERA and 192 strikeouts this season. Sanchez is 2-0 with a 3.57 ERA and 16 strikeouts in his career against the Los Angeles Dodgers.

Los Angeles Dodgers Betting Preview


The Los Angeles Dodgers are 84-66 on the year and play the Giants, Diamondbacks, and Mariners next. The Los Angeles Dodgers are batting .254 on the season, have a .330 OBP, and a .436 slugging percentage. The Los Angeles Dodgers pitching staff has a 4.04 ERA and a 1.27 WHIP. Shohei Ohtani leads the Los Angeles Dodgers with 159 hits and 93 RBI while Freddie Freeman and Andy Pages have combined for 301 hits and 163 RBI.

Shohei Ohtani gets the ball for the Los Angeles Dodgers, and he is 1-1 with a 3.75 ERA and 49 strikeouts this season. This will be Ohtani’s first career game against the Philadelphia Phillies.

Philadelphia Phillies @ Los Angeles Dodgers Betting Trends: September 16, 2025


  • Probable Starting Pitcher: Shohei Ohtani      Record this season: 1-1      ERA: 3.75
  • Home Record: 1-0
  • Last 5 against Phillies: –

Why the Los Angeles Dodgers will win

  • The Dodgers have won each of their last seven games at Dodger Stadium following an extra innings loss.
  • The Phillies have lost each of their last three games against NL West opponents following a win.
  • The Phillies have failed to cover the run line in five of their last six games as underdogs against National League opponents following a win.
  • The Dodgers have covered the run line in five of their last six games as favorites after playing the previous day.
  • The Phillies have trailed after 5 innings in nine of their last 10 road games against opponents that held a winning record.

  • Probable Starting Pitcher: Cristopher Sanchez      Record this season: 13-5      ERA: 2.57
  • Road Record: 7-5
  • Last 5 against Dodgers: 2-0

Why the Philadelphia Phillies will win

  • The Phillies have won seven of their last eight games as underdogs.
  • The Dodgers have lost each of their last seven night games against the Phillies following a loss.
  • The Dodgers have failed to cover the run line each of their last seven games against NL East opponents that held a winning record.
  • The Phillies have covered the run line each of their last six games against National League opponents that held a winning record.
  • The Phillies have won the first inning in three of their last four road games.

Total Runs Facts

  • Each of the Phillies’ last seven games after playing the previous day have gone OVER the total runs line.
  • Seven of the Dodgers’ last eight games following an extra innings loss have gone OVER the total runs line.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Phillies’ last six night games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Dodgers’ last seven night games at Dodger Stadium.

Los Angeles Dodgers Player Prop Facts

  • Andy Pages has recorded at least one hit in each of the Dodgers’ last 12 games as favorites against NL East opponents.
  • Mookie Betts has hit a home run in each of the Dodgers’ last three games at Dodger Stadium.
  • Esteury Ruiz has recorded a Double in each of his three previous appearances against the Phillies.

Philadelphia Phillies Player Prop Facts

  • Kyle Schwarber has hit at least one home run in each of the Phillies’ last three road games against the Dodgers.
  • Trea Turner has recorded at least one hit in each of his last 15 road appearances against NL opponents.

Matchup/League Facts

  • The Dodgers rank 2nd in the league for RBIs this season (735).
  • The Dodgers rank 2nd in the league for slugging percentage this season (.439).
  • The Phillies rank 2nd in the league for strikeouts this season (1376).
  • The Phillies rank 2nd in the league for walks allowed this season (412).

Philadelphia Phillies vs Los Angeles Dodgers Prediction


The Dodgers are going to be favored because they’re the Dodgers, and they’re at home with Ohtani on the mound. However, Ohtani has been hittable lately, allowing 21 hits and 11 runs in his last 21 innings. The Phillies are too good and too hot to turn down at a reasonable price, and Sanchez has been an all-star caliber pitcher this season. Sanchez has allowed 17 hits and 3 runs in his last 20 innings. In 97.1 road innings, Sanchez has a 2.87 ERA and .249 allowed batting average. I’m going to back the Phillies again.

Randy Chambers's Pick: Philadelphia Phillies

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