Philadelphia Phillies vs Chicago White Sox Prediction 07/30/2025 MLB Picks

The Philadelphia Phillies and Chicago White Sox meet Wednesday in MLB action at Rate Field. Here’s a Philadelphia Phillies vs Chicago White Sox Prediction. This article will include a Philadelphia Phillies vs Chicago White Sox Pick.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 61-46 on the year and play the Tigers, Orioles, and Rangers next. The Philadelphia Phillies are batting .255 on the season, have a .328 OBP, and a .413 slugging percentage. The Philadelphia Phillies pitching staff has a 3.76 ERA and a 1.25 WHIP. Trea Turner leads the Philadelphia Phillies with 127 hits and 44 RBI, while Nick Castellanos and Kyle Schwarber have combined for 208 hits and 143 RBI. 

Taijuan Walker gets the ball for the St. Louis Cardinals, and he is 3-5 with a 3.84 ERA and 56 strikeouts this season. Walker is 3-2 with a 3.64 ERA and 19 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 39-69 on the year and play the Angels, Mariners, and Guardians next. The Chicago White Sox are batting .226 on the season, have a .298 OBP, and a .360 slugging percentage. The Chicago White Sox pitching staff has a 4.10 ERA and a 1.38 WHIP. Lenyn Sosa leads the Chicago White Sox with 89 hits and 40 RBI while Miguel Vargas and Chase Meidroth have combined for 164 hits and 56 RBI.

Adrian Houser gets the ball for the Chicago White Sox, and he is 6-2 with a 2.10 ERA and 47 strikeouts this season. Houser is 1-2 with a 3.90 ERA and 15 strikeouts in his career against the Philadelphia Phillies.

Why the Chicago White Sox will win

• The Phillies have lost five of their last six games as favorites against AL Central opponents following a road win.
• The White Sox have won each of their last three games as home underdogs against NL East opponents following a loss.
• The White Sox have covered the run line in each of their last seven games as underdogs following a loss.
• The Phillies have failed to cover the run line in five of their last six games as favorites against AL Central opponents following a win.
• The White Sox have led after 5 innings in three of their last four day games against NL East opponents that held a winning record.

Why the Philadelphia Phillies will win

• The Phillies have won 10 of their last 11 day games against AL Central opponents that held a losing record.
• The White Sox have lost four of their last five home games against NL East opponents that held a winning record.
• The Phillies have covered the run line in nine of their last 10 day games against AL Central opponents that held a losing record.
• The White Sox have failed to cover the run line in four of their last five games at Rate Field against NL East opponents that held a winning record.
• The White Sox have trailed after 5 innings in four of their last five games at Rate Field against NL East opponents that held a winning record.

Chicago White Sox Player Prop Facts

• Andrew Benintendi has hit at least one home run in three of his last four appearances in day games against teams that held a winning record.
• Adrian Houser has recorded five or more strikeouts in four of his last five appearances against NL opponents.
• Adrian Houser has recorded a win in each of his six previous appearances at Rate Field against opponents that held a winning record.
• Korey Lee has recorded at least one hit in each of his seven previous appearances with the White Sox as underdogs against NL East opponents.

Philadelphia Phillies Player Prop Facts

• Taijuan Walker has recorded a win in each of his last four appearances in day games against AL teams that held a losing record.
• Brandon Marsh has recorded a Double in three of his last four appearances with the Phillies as favorites against AL Central opponents.
• Alec Bohm has recorded at least one hit in 19 of his last 20 road appearances against opponents that held a losing record.
• Brandon Marsh has hit a home run in three of his last five appearances with the Phillies as favorites against the White Sox.
• Taijuan Walker has recorded four or more strikeouts in 14 of his last 17 appearances against AL opponents that held a losing record.

Philadelphia Phillies vs Chicago White Sox Prediction

The Phillies should be favored considering they’re the better team and Walker has been respectable with a 3.84 ERA and 1.35 WHIP. However, the White Sox have done enough winning in the second half to deserve a look, and they’ve won six straight games Houser has pitched. Houser has allowed 26 hits and seven earned runs in his last 26 innings. In 32.2 home innings, Houser has a 1.38 ERA and .216 allowed batting average. I’ll take another shot with the White Sox at home.