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Philadelphia Phillies vs Chicago White Sox Prediction 07/30/2025 MLB Picks

Jul 29, 2025; Chicago, Illinois, USA;  Chicago White Sox first baseman Miguel Vargas (20) tries to make the catch on the foul ball hit by Philadelphia Phillies catcher J.T. Realmuto (10) during the seventh inning at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

Jul 29, 2025; Chicago, Illinois, USA; Chicago White Sox first baseman Miguel Vargas (20) tries to make the catch on the foul ball hit by Philadelphia Phillies catcher J.T. Realmuto (10) during the seventh inning at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Philadelphia Phillies Chicago White Sox
Team Records 61-46 39-69
Where Rate Field, Chicago, Illinois
When Wednesday, July 30, 2025
Time 02:10 PM EDT
TV MLB.TV

The Philadelphia Phillies and Chicago White Sox meet Wednesday in MLB action at Rate Field. Here’s a Philadelphia Phillies vs Chicago White Sox Prediction. This article will include a Philadelphia Phillies vs Chicago White Sox Pick.

Philadelphia Phillies Betting Preview

The Philadelphia Phillies are 61-46 on the year and play the Tigers, Orioles, and Rangers next. The Philadelphia Phillies are batting .255 on the season, have a .328 OBP, and a .413 slugging percentage. The Philadelphia Phillies pitching staff has a 3.76 ERA and a 1.25 WHIP. Trea Turner leads the Philadelphia Phillies with 127 hits and 44 RBI, while Nick Castellanos and Kyle Schwarber have combined for 208 hits and 143 RBI. 

Taijuan Walker gets the ball for the St. Louis Cardinals, and he is 3-5 with a 3.84 ERA and 56 strikeouts this season. Walker is 3-2 with a 3.64 ERA and 19 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 39-69 on the year and play the Angels, Mariners, and Guardians next. The Chicago White Sox are batting .226 on the season, have a .298 OBP, and a .360 slugging percentage. The Chicago White Sox pitching staff has a 4.10 ERA and a 1.38 WHIP. Lenyn Sosa leads the Chicago White Sox with 89 hits and 40 RBI while Miguel Vargas and Chase Meidroth have combined for 164 hits and 56 RBI.

Adrian Houser gets the ball for the Chicago White Sox, and he is 6-2 with a 2.10 ERA and 47 strikeouts this season. Houser is 1-2 with a 3.90 ERA and 15 strikeouts in his career against the Philadelphia Phillies.

Why the Chicago White Sox will win

Why the Philadelphia Phillies will win

Chicago White Sox Player Prop Facts

Philadelphia Phillies Player Prop Facts

Philadelphia Phillies vs Chicago White Sox Prediction

The Phillies should be favored considering they’re the better team and Walker has been respectable with a 3.84 ERA and 1.35 WHIP. However, the White Sox have done enough winning in the second half to deserve a look, and they’ve won six straight games Houser has pitched. Houser has allowed 26 hits and seven earned runs in his last 26 innings. In 32.2 home innings, Houser has a 1.38 ERA and .216 allowed batting average. I’ll take another shot with the White Sox at home. 

Randy Chambers's Pick: Chicago White Sox

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