San Diego (55-45) vs Miami (46-53)
July 22, 2025 at 06:40 PM EDT
The Line: Betting Odds: Miami -110 — Over/Under: 8
In this article, we will formulate a Padres vs Marlins prediction for this MLB game on Tuesday, July 22nd at loanDepot park in Miami, Florida. Let’s take a look at the prediction for this MLB matchup.
San Diego Padres Betting Preview
The San Diego Padres are 55-45 this year after they won game one by a score of 2-1 on Monday night. San Diego scored both of their runs in the second inning, and they were able to get the win, but they went scoreless over the last seven innings. The Padres recorded five hits in the game, and they were led by Merrill and Maldonado, who both had one RBI in the win. San Diego started Vasquez, who allowed seven hits and one earned run over 4.1 innings, while Morejon picked up the win and Suarez got the save.
Prior to this series, the Padres won two out of three against the Nationals and two out of three against the Phillies. San Diego has won six of their last eight games, and they are currently second in the NL West standings. The San Diego pitching staff has a 3.58 ERA with a 1.23 WHIP and a .229 opponent batting average, while their offense has scored 402 runs with a .246 batting average and a .316 on-base percentage this season. Manny Machado has led San Diego with 18 home runs and 60 RBIs, while Fernando Tatis has added 16 home runs and 42 RBIs this year. The projected starting pitcher for San Diego is Stephen Kolek, who is 3-4 with a 4.24 ERA and a 1.29 WHIP over 68.0 innings pitched this year.
Miami Marlins Betting Preview
The Miami Marlins are 46-53 this season after they lost game one by a score of 2-1 to open the series. Miami cut the deficit to 2-1 in the fourth inning, but they failed to score any more runs for the loss. The Marlins recorded nine hits in the game, and they were led by Stowers, who went 1-4 with one home run and one RBI in the loss. Miami started Perez, who allowed five hits and two earned runs over 5.0 innings for the loss, while Simpson and Phillips pitched two scoreless innings each.
Prior to this series, the Marlins won two out of three against the Royals and two out of three against the Orioles. Miami has won four of its last six games, and they are currently third in the NL East standings. The Miami pitching staff has a 4.53 ERA with a 1.32 WHIP and a .251 opponent batting average, while the offense has scored 424 runs with a .253 batting average and a .315 on-base percentage this season. Kyle Stowers has led Miami with 22 home runs and 60 RBIs, while Agustin Ramirez has added 14 home runs and 44 RBIs this year. The projected starting pitcher for Miami is Edward Cabrera, who is 3-4 with a 3.61 ERA and a 1.26 WHIP over 82.1 innings pitched this season.
Why the Marlins will beat the Padres
The Padres have lost seven of their last eight road games following a win.
The Marlins have won five of their last six games following a home loss.
The Marlins have covered the run line in six of their last seven games against National League opponents following a home loss.
The Padres have failed to cover the run line in five of their last six road games against NL East opponents following a win.
Total Runs Facts
Six of the Padres’ last seven night games against NL East opponents have gone UNDER the total runs line.
Five of the Marlins’ last six games against NL West opponents have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Padres’ last seven night games.
The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Marlins’ last six night games.
Miami Marlins Player Prop Facts
Edward Cabrera has recorded six strikeouts in three of his last four appearances.
Kyle Stowers has hit a home run in each of the Marlins’ last two night games against NL West opponents that held a winning record.
Otto Lopez has recorded at least one hit in each of his last 11 Tuesday appearances against teams that held a winning record.
San Diego Padres Player Prop Facts
Jackson Merrill has hit a home run in two of his three previous road appearances against the Marlins after playing the previous day.
Luis Arraez has recorded at least one hit in each of his last 10 appearances at LoanDepot Park.
Xander Bogaerts has recorded a Double in three of the Padres’ last four night games against NL opponents that held a losing record.
Padres vs Marlins Prediction
San Diego was able to get a very low-scoring win on Monday night, as they continue to try and catch the Dodgers in the NL West. The Padres are 24-27 on the road this year, while the Marlins are 22-29 at home. Miami has lost two games in a row, but they are starting Cabrera, who has allowed two earned runs or fewer in four of his last five starts. The Padres are going with Kolek, who is being recalled from the minors, but hasn’t been very sharp. Take the Marlins at home here.