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Orioles vs Red Sox Prediction 5/24/25 MLB Picks

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Boston Red Sox (26-26) vs Baltimore Orioles (16-33)

May 24, 2025 at 01:05 PM EDT

The Line: Betting Odds: Boston Red Sox +0.0001 / Baltimore Orioles +0.0001 — Over/Under: 0.0001

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In this article we will formulate an Orioles vs Red Sox prediction for this MLB game on Saturday, May 24th at Fenway Park in Boston, Massachusetts. Let’s take a look at the prediction for this MLB doubleheader. 

Baltimore Orioles Betting Preview

The Baltimore Orioles are 16-33 this season after they lost game one in this series by a score of 19-5. Baltimore led 2-0 in the third inning, but their pitching staff fell apart in the sixth and eighth innings for the blowout loss. The Orioles recorded 14 hits and they committed two errors in the game, while they were led by Holliday, who went 2-5 with two RBIs in the loss. Baltimore started Povich, who allowed four hits and one earned run over 5.0 innings, while Perez and Rivera combined to allow 13 earned runs in relief. 

Prior to this series, the Orioles lost two out of three against the Brewers and all three against the Nationals. Baltimore has lost nine of their last ten games and they are currently last in the AL East standings. The Baltimore pitching staff has a 5.75 ERA with a 1.51 WHIP and a .278 opponent batting average, while their offense has scored 188 runs with a .235 batting average and a .301 on base percentage this season. Cedric Mullins has led Baltimore with 10 home runs and 31 RBIs, while Ryan O’Hearn has added seven home runs and 16 RBIs this year. The projected starting pitcher for game one is Zach Eflin, who is 3-2 with a 5.08 ERA and a 1.13 WHIP over 28.1 innings pitched this year. The projected starting pitcher for game two is Trevor Rogers, who is making his first appearance for Baltimore this year. 

Boston Red Sox Betting Preview

The Boston Red Sox are 26-26 this year after they won game one by a score of 19-5 on Friday afternoon. Boston had their lead cut to 6-3 in the top of the eighth inning, but they scored 13 runs in the bottom of the inning to put the game away. The Red Sox recorded 20 hits in the game and they were led by Devers, who went 4-6 with two home runs and eight RBIs in the win. Boston started Bello, who allowed six hits and two earned runs over 4.0 innings, while Whitlock picked up the win in relief. 

Prior to this series, the Red Sox won two out of three against the Mets, but lost two out of three against the Braves before that. Boston has won three of their last four games and they are currently tied for second in the AL East standings. The Boston pitching staff has a 4.05 ERA with a 1.35 WHIP and a .259 opponent batting average, while their offense has scored 259 runs with a .257 batting average and a .329 on base percentage this season. Rafael Devers has led Boston with 12 home runs and 47 RBIs, while Alex Bregman has added 11 home runs and 35 RBIs this year. The projected starting pitcher for Boston in game one is Hunter Dobbins, who is 2-1 with a 3.62 ERA and a 1.30 WHIP over 32.1 innings pitched. The projected starting pitcher for game two is Lucas Giolito, who is 1-1 with a 7.08 ERA and a 1.52 WHIP over 20.1 innings pitched this year. 

Why the Red Sox will beat the Orioles

  • The Orioles have lost nine of their last 10 games.
  • The Red Sox have won four of their last five day games against AL East opponents.
  • The Red Sox have covered the run line in seven of their last eight games against American League opponents after playing the previous day.
  • The Orioles have failed to cover the run line in seven of their last eight games against AL East opponents.

Total Runs Facts

  • Each of the Orioles’ last five day games against AL East opponents have gone OVER the total runs line.
  • Five of the Red Sox’s last six home games against AL East opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Orioles’ last four games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Red Sox’s last six home games against AL East opponents.

Boston Red Sox Player Prop Facts

  • Trevor Story has recorded at least one hit in each of his last nine appearances in day games against teams that held a losing record.
  • Rafael Devers has recorded two or more RBIs in each of the Red Sox’s last four day games.
  • Rafael Devers has scored at least one run in each of the Red Sox’s last four day games.
  • Rafael Devers has hit at least one home run in five of his last six appearances in day games against AL East teams that held a losing record.
  • Connor Wong has recorded a Double in three of his last four appearances in day games against AL teams that held a losing record.
  • Ceddanne Rafaela has recorded at least one Single in eight of the Red Sox’s last nine games against the Orioles.

Baltimore Orioles Player Prop Facts

  • Zach Eflin has recorded a win in six of his last eight road appearances.
  • Gunnar Henderson has recorded at least one hit in each of the Orioles’ last 10 games at Fenway Park.
  • Ryan Mountcastle has recorded an RBI in four of the Orioles’ last five road games against AL opponents.
  • Jorge Mateo has scored at least one run in five of his last six road appearances against the Red Sox.
  • Jordan Westburg has hit a home run in two of his last three appearances against the Red Sox at Fenway Park.
  • Gunnar Henderson has recorded a Double in three of the Orioles’ last four road games against the Red Sox.
  • Ryan O’Hearn has recorded at least one Single in seven of the Orioles’ last eight road games against AL East opponents.

Orioles vs Red Sox Prediction 

Boston was able to erupt for 19 runs in their win on Friday afternoon and they will look to continue that hot hitting during this doubleheader. The Red Sox are 15-12 at home this year, while the Orioles are 8-18 on the road. Baltimore continues to be the worst team in the AL East and they haven’t shown many signs of turning things around. In game one, I don’t like what I saw from Eflin in his last start, so I will take Boston to win. In game two, I don’t trust either starting pitcher, especially Giolito, so I like the over to finish the doubleheader. 

David Racey's Pick: Game 1: Red Sox ML Game 2: Over 9.5

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