Oakland Athletics vs San Francisco Giants Prediction 5/17/25 MLB Picks

In this article, we will formulate an Athletics vs Giants prediction for this MLB game on Saturday, May 17, at Oracle Park in San Francisco, California. Let’s take a look at the prediction for this MLB matchup.

Athletics Betting Preview

The Athletics (22-23, 14-10 Away) lost seven of the previous nine games, losing the series to the Mariners, Yankees, and Dodgers along the way. Including last night’s 9-1 defeat to the San Francisco Giants in Game 1 of the current series, the A’s are now on a three-game losing skid. JP Sears took the loss after allowing four runs on six hits with two strikeouts and three walks in 4.0 innings.

This year, the Athletics average 4.38 runs per game (14th in the MLB) on a .256/.315/.423 triple-slash. When it comes to pitching, the Athletics’ staff has a 5.28 ERA (26th) and 1.51 WHIP (29th). Tyler Soderstrom leads the Athletics with a .279 batting average, ten home runs, and 30 RBI this season.

The projected starting pitcher for the Athletics is Luis Severino, who is 1-4 in nine starts this season, with a 4.70 ERA and 1.32 WHIP in 53.2 innings.

San Francisco Giants Betting Preview

The San Francisco Giants (26-19, 14-7 Home) defeated the Chicago Cubs and then were swept by the Twins and lost the series to the Diamondbacks. The Giants responded well in Game 1, a 9-1 victory over the Athletics, outhitting the visitors 13-5. Wilmer Flores had a game of his life as he blasted a grand slam, a three-run homer, and a solo homer to lead the offense with a career-high eight RBI. Logan Webb got the win after allowing one run on five hits with four strikeouts and two walks across 8.0 innings of work.

This season, the Giants average 4.84 runs per game (8th in the MLB) on a .239/.315/.393 triple-slash. When it comes to pitching, the Giants’ staff has a 3.48 ERA (8th) and 1.23 WHIP (12th). Wilmer Flores leads the Giants with a .266 batting average, ten home runs, and 41 RBI this season.

Landen Roupp will take the mound for the Giants on Saturday. The 26-year-old right-hander has a 2-3 record in eight starts this year with a 4.95 ERA and 1.50 WHIP in 55.1 innings.

Total Runs Facts

• Each of the Athletics’ last nine night games against NL West opponents have gone OVER the total runs line.
• Five of the Giants’ last six night games against AL West opponents have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 12 of the Giants’ last 14 night games against AL West opponents.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Athletics’ last five night games at Oracle Park.

Matchup/League Facts

• The Giants rank 8th in the league for RBIs this season (208).
• The Giants rank T23rd in the league for steals this season (25).
• The Athletics rank 29th in the league for runs allowed this season (256).
• The Athletics rank T28th in the league for steals this season (19).

Athletics vs Giants Prediction

The Giants won six of the previous ten H2H encounters, including three of the last four. Nine of the Athletics’ last ten games went Over, which was the case in six of San Francisco’s previous ten. I am going with another Over here because I don’t trust Severino and Roupp. Severino allowed 4+ runs in four starts this season, and he surrendered 12 runs in his last two starts. Roupp, on the other hand, allowed multiple runs in all but one start this year, so I am backing both offenses to score multiple runs off these starters early on. I expect to see at least eight combined runs.