New York (66-57) vs St. Louis (61-63)
August 17, 2025 at 02:15 PM EDT
The Line: Betting Odds: St. Louis +1.5 — Over/Under: +9.5
The New York Yankees and St. Louis Cardinals meet Sunday in MLB action at Busch Stadium. Here’s a New York Yankees vs St. Louis Cardinals Prediction. This article will include a New York Yankees vs St. Louis Cardinals Pick.
New York Yankees Betting Preview
The New York Yankees are 66-57 on the year and play the Rays, Red Sox, and Nationals next. The New York Yankees are batting .250 on the season, have a .330 OBP, and a .447 slugging percentage. The New York Yankees pitching staff has a 4.04 ERA and a 1.25 WHIP. Aaron Judge leads the New York Yankees with 136 hits and 91 RBI, while Cody Bellinger and Paul Goldschmidt have combined for 227 hits and 109 RBI.
Will Warren gets the ball for the New York Yankees, and he is 7-5 with a 4.34 ERA and 140 strikeouts this season. This will be Warren’s second career game against the St. Louis Cardinals.
St. Louis Cardinals Betting Preview
The St. Louis Cardinals are 61-63 on the year and play the Marlins, Rays, and Pirates next. The St. Louis Cardinals are batting .250 on the season, have a .318 OBP, and a .383 slugging percentage. The St. Louis Cardinals pitching staff has a 4.25 ERA and a 1.29 WHIP. Brendan Donovan leads the St. Louis Cardinals with 118 hits and 45 RBI while Masyn Winn and Alec Burleson have combined for 223 hits and 100 RBI.
Miles Mikolas gets the ball for the St. Louis Cardinals, and he is 6-9 with a 4.97 ERA and 79 strikeouts this season. Mikolas is 1-0 with a 3.97 ERA and 8 strikeouts in his career against the New York Yankees.
Why the St. Louis Cardinals will win
- The Yankees have lost three of their last four games as road favorites against National League opponents following a win.
- The Cardinals have won 14 of their last 19 games as home underdogs following a home loss.
- The Yankees have failed to cover the run line in seven of their last eight games as road favorites.
- The Cardinals have covered the run line in six of their last seven games as underdogs against American League opponents following a home loss.
- The Yankees have trailed after 5 innings in three of their last four day games against National League opponents.
- The Yankees have trailed after 3 innings in four of their last five games as road favorites.
Why the New York Yankees will win
- The Cardinals have lost each of their last six home games against AL East opponents that held a winning record.
- The road team has won each of the last four games between the Yankees and Cardinals.
- The Cardinals have failed to cover the run line in eight of their last nine home games against American League opponents that held a winning record.
- The Yankees have covered the run line in five of their last six day games against NL Central opponents that held a losing record.
- The Yankees have won the first inning in four of their last five games as road favorites.
- The Yankees have led after 5 innings in each of their last four games as road favorites against NL Central opponents.
St. Louis Cardinals Player Prop Facts
- Miles Mikolas has recorded four or more strikeouts in five of his last six appearances in day games against teams that held a winning record.
- Masyn Winn has recorded at least one hit in each of his 13 previous home appearances against AL East opponents.
- Nolan Arenado has hit a home run in three of his last five appearances with the Cardinals as home underdogs against AL opponents.
- Nolan Arenado has recorded a Double in each of his last three appearances against the Yankees at Busch Stadium.
New York Yankees Player Prop Facts
- Aaron Judge has hit a home run in each of his last two road appearances against opponents that held a losing record.
- Giancarlo Stanton has recorded a Double in each of his three previous appearances with the Yankees as favorites against the Cardinals.
- Paul Goldschmidt has recorded two or more hits in five of his last six appearances against NL Central opponents that held a losing record.
- Aaron Judge ranks 1st amongst qualified players for Slugging Percentage (.689) this season.
New York Yankees vs St. Louis Cardinals Prediction
The Yankees have found their form this week, and they’re throwing out Warren, who has allowed 12 hits and three runs in his last 17.2 innings. The Cardinals are having a week from hell and Mikolas is having an off season with a 4.97 ERA and 1.28 WHIP. Mikolas has allowed 11 hits and seven runs in his last 9.2 innings. The Cardinals have lost seven of Mikolas’ last 11 starts. I have to side with the Yankees for the sweep.