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New York Yankees vs San Francisco Giants Prediction 3/28/2026 Today’s MLB Picks

MATCHUP New York Yankees San Francisco Giants
Team Records 2-0 0-2
Spread -1.5 129 +1.5 -156
Moneyline -131 +109
Total Over 8.5 (-110) Under 8.5 (-110)
Where Oracle Park, San Francisco, California
When Saturday, March 28, 2026
Time 07:15 PM EDT
TV MLB.TV
The New York Yankees and the San Francisco Giants meet Saturday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Yankees vs. San Francisco Giants prediction.

Starting Pitching Matchup

The New York Yankees send out Will Warren for the start here and Warren was 9-8 with a 4.44 ERA and 171 strikeouts last season. This will be Warren’s first career start against the Giants. Tyler Mahle will start for the Giants and was 6-4 with a 2.18 ERA and 66 strikeouts last season. This will be Mahle’s second career start against the Yankees.

New York Yankees Recap

The New York Yankees come into this game looking to add on to their 3-0 win over the Giants from Friday’s matchup to improve to 2-0 on the year. After this series, the Yankees will take to the road for a series against the Seattle Mariners.

Yankees Looking For Early Season Series Win

Giancarlo Stanton leads the Yankees with 4 hits including a home run and two RBIs while Jose Caballero has 3 hits with an RBI as well. Austin Wells, Cody Bellinger and Jazz Chisholm Jr. all have a pair of hits while Aaron Judge has a home run and 2 RBIs. Paul Goldschmidt’s added a double while Trent Grisham has a triple and 2 RBIs and Ryan McMahon has 2 RBIs as well on the year. 

San Francisco Giants Recap

The San Francisco Giants will be out to rebound from the loss to the Yankees on Friday to fall to 0-2 this season. After this series, the Giants will head on the road for a game against the San Diego Padres.

Giants Still Searching For First Run Of 2026

Heliot Ramos leads San Francisco with 2 hits so far this season as part of his .286 batting average along with a double while Rafael Devers has gone 1 for 8 and Luis Arraez is 1 for 7 at the dish. Willy Adames and the aforementioned Ramos each have a team-high 4 strikeouts so far this season.

New York Yankees @ San Francisco Giants Betting Trends: March 28, 2026


Why the San Francisco Giants will win


Why the New York Yankees will win

Total Runs Facts

San Francisco Giants Player Prop Facts

New York Yankees Player Prop Facts

Matchup/League Facts

New York Yankees vs. San Francisco Giants Prediction

I’m on the Yankees here. It’s just really hard for me to make a case for a team like San Fran in this spot when the Giants have yet to score a run this season. San Francisco will turn it around at some point I’m sure, but it’s scary that the Yankees can do this without a whole ton of production from Aaron Judge in the first two games and the pitching has been on point. Give me New York.

Chris Ruffolo's Pick: New York -160

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