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New York Yankees vs Pittsburgh Pirates Prediction 4/4/25 MLB Picks

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Pittsburgh Pirates (2-5) vs New York Yankees (4-2)

Game Info: Friday, April 4, 2025 at 4:12 pm (PNC Park)

The Line: Betting Odds: Pittsburgh Pirates +136 / New York Yankees -162 — Over/Under: 8

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In this article, we will formulate a Yankees vs Pirates prediction for this MLB game on Friday, April 4, at PNC Park in Pittsburgh, Pennsylvania. Let’s take a look at the prediction for this MLB matchup.

New York Yankees Betting Preview

The New York Yankees (4-2, 0-0 Away) opened the new season in style with a series sweep of the Milwaukee Brewers. The Yankees scored an unbelievable 36 runs in that three-game series but lost the next two games against the Arizona Diamondbacks. New York was on the brink of being swept but managed to win 9-7 in Game 3 to conclude the series. Aaron Judge hit four RBI, and Carlos Carrasco took a win after allowing three runs on five hits with five strikeouts and two walks in 5.1 innings.

This year, the Yankees average 8.80 runs per game (1st in the MLB) on a .266/.345/.633 triple-slash. When it comes to pitching, the Yankees’ staff has a 4.20 ERA (17th) and 1.24 WHIP (17th). Aaron Judge leads the Yankees with a .417 batting average, five home runs, and 15 RBI this season.

Max Fried will take the mound for the Yankees on Friday. The 31-year-old southpaw had an 11-10 record last season in 29 starts with a 3.25 ERA and 1.16 WHIP in 174.1 innings for the Atlanta Braves. This season, Fried posted a 3.86 ERA in 4.2 innings in his first start of the season against the Brewers.

Pittsburgh Pirates Betting Preview

The Pittsburgh Pirates (2-5, 0-0 Home) lost the first two series of the season to the Miami Marlins and Tampa Bay Rays. They got a win in each of the series, including the most recent 4-2 victory over the Rays, to avoid the series sweep. Oneil Cruz contributed offensively with a pair of RBI, while Paul Skenes secured a win after allowing no earned runs on three hits with six strikeouts and no walks in 7.0 innings.

This season, the Pirates average 2.71 runs per game (25th in the MLB) on a .197/.291/.278 slash line. Regarding pitching, the Pirates’ staff has a 3.96 ERA (15th) and 1.40 WHIP (22nd). Oneil Cruz leads the Pirates with a .261 batting average, two home runs, and four RBI this season.

The projected starting pitcher for the Pirates is Mitch Keller, who had an 11-12 record in 31 starts last season with a 4.25 ERA and 1.30 WHIP over 178.0 innings of work. Keller registered a win against the Marlins this season with a 1.50 ERA over 6.0 innings of work.

Why the New York Yankees will win

Total Runs Facts

Yankees vs Pirates Prediction

The Yankees won six of the previous ten H2H encounters, but the Pirates won three of the last four. Mitch Keller had a strong start in his first game of the season, but against the Yankees, he allowed a .339 BA in 62 at-bats so far in his career. Fried has better numbers against the Pirates; he allowed a .247 BA at 93 at-bats. The Yankees have hit the Moneyline in 11 of their last 16 away games, and I am backing them to win here as well. It’s not going to be a comfortable win, but the Yankees will prevail.

Oliver Zivic's Pick: Yankees ML

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