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New York Yankees vs Houston Astros Prediction 9/3/2025 Today’s MLB Picks

Sep 2, 2025; Houston, Texas, USA; New York Yankees second baseman Jazz Chisholm Jr. (13) celebrates with third baseman Amed Rosario (14) after hitting a home run during the eighth inning against the Houston Astros at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

Sep 2, 2025; Houston, Texas, USA; New York Yankees second baseman Jazz Chisholm Jr. (13) celebrates with third baseman Amed Rosario (14) after hitting a home run during the eighth inning against the Houston Astros at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

New York (77-61) vs Houston (76-63)

September 3, 2025 at 08:10 PM EDT

The Line: Betting Odds: Houston +1.5 — Over/Under: +9

(Get latest betting odds)

The New York Yankees and Houston Astros meet Wednesday in MLB action at Daikin Park. Here’s a New York Yankees vs Houston Astros Prediction. This article will include a New York Yankees vs Houston Astros Pick.

New York Yankees Betting Preview

The New York Yankees are 77-61 on the year and play the Blue Jays, Tigers, and Red Sox next. The New York Yankees are batting .250 on the season, have a .331 OBP, and a .457 slugging percentage. The New York Yankees pitching staff has a 3.90 ERA and a 1.25 WHIP. Aaron Judge leads the New York Yankees with 151 hits and 97 RBI, while Cody Bellinger and Paul Goldschmidt have combined for 261 hits and 126 RBI.

Will Warren gets the ball for the New York Yankees, and he is 8-6 with a 4.30 ERA and 149 strikeouts this season. This will be Warren’s first career game against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 76-63 on the year and play the Rangers, Blue Jays, and Braves next. The Houston Astros are batting .252 on the season, have a .318 OBP, and a .400 slugging percentage. The Houston Astros pitching staff has a 3.84 ERA and a 1.22 WHIP. Jose Altuve leads the Houston Astros with 141 hits and 68 RBI while Jeremy Pena and Christian Walker have combined for 248 hits and 125 RBI.

Jason Alexander gets the ball for the Houston Astros, and he is 4-1 with a 4.61 ERA and 46 strikeouts this season. Alexander is 1-0 with a 2.79 ERA and 8 strikeouts in his career against the New York Yankees.

New York Yankees vs Houston Astros Prediction

We have two playoff teams and two pitchers in great form. You’d think this was going to be a tight, low scoring game. I’m going with the over. While Warren has allowed eight earned runs in his last 25.1 innings, he has a 5.58 ERA and .280 allowed batting average in 59.2 road innings. Alexander has allowed 22 hits and seven runs in his last 29 innings, but he has a 5.40 ERA and .307 allowed batting average in 25 home innings. We know what these lineups can do, and these home/road splits are nasty. Expect fireworks. Give me the over.

Randy Chambers's Pick: Over 9

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