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New York Yankees vs Chicago White Sox Prediction 8/29/2025 Today’s MLB Picks

Aug 28, 2025; Chicago, Illinois, USA;  New York Yankees outfielder Cody Bellinger (35) slides safely past Chicago White Sox catcher Kyle Teel (8) during the ninth inning at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

Aug 28, 2025; Chicago, Illinois, USA; New York Yankees outfielder Cody Bellinger (35) slides safely past Chicago White Sox catcher Kyle Teel (8) during the ninth inning at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

New York (74-60) vs Chicago (48-86)

August 29, 2025 at 07:40 PM EDT

The Line: Betting Odds: Chicago +183 — Over/Under: +9

(Get latest betting odds)

In this article, we will formulate a Yankees vs White Sox Prediction for this MLB game on Friday, August 29th at the Rate Field in the second game of this series, with the Yankees having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Chicago White Sox Preview

The Chicago White Sox have a 48-86 record this season and are sitting on the last place of the AL Central. The White Sox have a 29-40 home record and are 62-64 in over/under. They are coming off a 4-10 home defeat by the Yankees, and have three consecutive losses. Over is 5-2 in their last 7 games and are playing the Twins and the Tigers next.

The White Sox have a .233 batting average this season, .302 OBP and .373 Slugging percentage. Chicago’s pitching staff has a 4.23 ERA and 1.37 WHIP. Lenyn Sosa leads the White Sox with 114 hits, and he is the team’s best hitter with a .270 batting average. He also leads the team in RBI with 60, adding a team-high 17 home runs.

Yoendrys Gomez (R) is the projected starting pitcher for the White Sox, and he has a 3-1 record, 4.73 ERA and 1.48 WHIP.

New York Yankees Preview

The New York Yankees have a 74-60 record this season and are sitting on the third place of the AL East. The Yankees have a 33-32 road record and are 64-65 in over/under. They are coming off a 10-4 road victory over the White Sox, and have five consecutive wins. Over is 9-2 in their last 11 games and are playing the Astros and the Blue Jays next.

The Yankees have a .252 batting average this season, .332 OBP and .458 Slugging percentage. New York’s pitching staff has a 3.96 ERA and 1.26 WHIP. Aaron Judge leads the Yankees with 145 hits, adding team-highs both in RBI, with 95 and in home runs, with 41. He is also the team’s best hitter, with a .323 batting average.

Carlos Rodon (R) is the projected starting pitcher for the Yankees, and he has a 14-7 record, 3.24 ERA and 1.07 WHIP.

Why the Chicago White Sox will win

  • The Yankees have lost four of their last five games as favorites against American League opponents following a road win.
  • The White Sox have won 12 of their last 18 games as underdogs against American League opponents following a home loss.
  • The Yankees have failed to cover the run line in each of their last six Friday night games.
  • The White Sox have covered the run line in eight of their last 10 home games after playing the previous day.
  • The White Sox have led after 3 innings in six of their last eight games against American League opponents.

Why the New York Yankees will win

  • The Yankees have won each of their last eight games against teams that held a losing record.
  • The White Sox have lost five of their last six home games against AL East opponents that held a winning record.
  • The Yankees have covered the run line each of their last eight games against teams that held a losing record.
  • The White Sox have failed to cover the run line in five of their last six home games against AL East opponents that held a winning record.
  • The Yankees have led after 3 innings in seven of their last eight games against American League opponents that held a losing record.
  • The Yankees have won the first inning in five of their last six road games.
  • The Yankees have led after 5 innings in each of their last six games against opponents that held a losing record.

Total Runs Facts

  • Each of the Yankees’ last five road games have gone OVER the total runs line.
  • Five of the White Sox’s last six night games as underdogs have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the White Sox’s last seven games as home underdogs against AL East opponents.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in five of the Yankees’ last six road games.

Matchup/League Facts

  • The White Sox rank 29th in the league for walks allowed this season (487).
  • The White Sox rank 28th in the league for slugging percentage this season (.373).
  • The Yankees rank 1st in the league for runs scored this season (702).
  • The Yankees rank 1st in the league for home runs this season (228).

Yankees vs White Sox Prediction

The Yankees are 6-1 in their last 7 head-to-head meetings against the White Sox, and have won their last three meetings in Chicago. Over is 4-1 in their last 5 meetings.

In this Yankees vs White Sox Prediction, the Yankees are coming as -220 home favorites. The Yankees are on a roll right now, and with Rodon on the mound, it is hard to fade them against a terrible White Sox squad. Yankees’ offense is red-hot lately, with 10+ runs in three of their last four games, and with Rodon on the mound to keep Chicago’s bats in check, I expect them to get away with another dominating road win and cover the runline again today.

Nikos Lagouretos's Pick: New York Yankees -1.5

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