New York Mets vs St. Louis Cardinals Prediction 5/3/25 MLB Picks

The New York Mets and St. Louis Cardinals meet Saturday in MLB action at Busch Stadium. Here’s a New York Mets vs St. Louis Cardinals Prediction. This article will include a New York Mets vs St. Louis Cardinals Pick.

New York Mets Betting Preview

The New York Mets are 22-11 on the year and play the Diamondbacks, Cubs, and Pirates next. The New York Mets are batting .250 on the season, have a .329 OBP, and a .424 slugging percentage. The New York Mets pitching staff has a 2.69 ERA and a 1.22 WHIP. Pete Alonso leads the New York Mets with 40 hits and 30 RBI, while Francisco Lindor and Juan Soto have combined for 69 hits and 30 RBI. 

Tylor Megill gets the ball for the New York Mets, and he is 3-2 with a 1.74 ERA and 39 strikeouts this season. Megill is 1-1 with a 7.00 ERA and 10 strikeouts in his career against the St. Louis Cardinals.

St. Louis Cardinals Betting Preview

The St. Louis Cardinals are 14-19 on the year and play the Pirates, Nationals, and Phillies next. The St. Louis Cardinals are batting .256 on the season, have a .329 OBP, and a .395 slugging percentage. The St. Louis Cardinals’ pitching staff has a 4.31 ERA and a 1.26 WHIP. Brendan Donovan leads the St. Louis Cardinals with 40 hits and 17 RBI, while Lars Nootbaar and Willson Contreras have combined for 59 hits and 31 RBI.

Erick Fedde gets the ball for the St. Louis Cardinals, and he is 1-3 with a 4.68 ERA and 17 strikeouts this season. Fedde is 1-5 with a 6.51 ERA and 44 strikeouts in his career against the New York Mets.

Why the St. Louis Cardinals will win

• The Cardinals have won seven of their last eight games as home underdogs following a loss.
• The Mets have lost each of their last five games as road favorites following a road win.
• The Mets have failed to cover the run line in 11 of their last 12 day games against NL Central opponents following a road win.
• The Cardinals have covered the run line in seven of their last eight day games following a home loss.

Why the New York Mets will win

• The Mets have won each of their last six games against NL Central opponents.
• The Cardinals have lost seven of their last eight games against NL East opponents.
• The Cardinals have failed to cover the run line in each of their last six games against National League opponents after playing the previous day.
• The Mets have covered the run line in seven of their last eight games at Busch Stadium.
• The Cardinals have trailed after 3 innings in three of their last four day games against National League opponents that held a winning record.
• The Cardinals have trailed after 5 innings in four of their last five day games against NL East opponents that held a winning record.

St. Louis Cardinals Player Prop Facts

• Willson Contreras has hit a home run in seven of his last 21 appearances against NL East opponents.
• Masyn Winn has recorded a Double in three of his last four appearances against the Mets.
• Willson Contreras has recorded at least one RBI in each of his last four appearances at Busch Stadium against NL opponents that held a winning record.
• Masyn Winn has scored at least one run in each of his last seven appearances at Busch Stadium against NL opponents that held a winning record.
• Masyn Winn has recorded at least one Single in each of his last eight appearances at Busch Stadium against NL opponents that held a winning record.
• Erick Fedde has recorded four or more strikeouts in five of his last six home appearances against NL East opponents that held a winning record.
• Brendan Donovan has recorded at least one hit in each of the Cardinals’ last 11 games as home underdogs.
• Victor Scott II ranks T5th in the league in Steals (11) this season.

New York Mets Player Prop Facts

• Juan Soto has recorded a Double in each of the Mets’ last three games against opponents that held a losing record.
• Pete Alonso has hit a home run in four of the Mets’ last five games at Busch Stadium against NL Central opponents that held a losing record.
• Brandon Nimmo has recorded at least one RBI in five of the Mets’ last six games against opponents that held a losing record.
• Jeff McNeil has recorded at least one Single in each of the Mets’ last seven road games against the Cardinals.
• Pete Alonso has scored at least one run in eight of the Mets’ last nine road games against opponents that held a losing record.
• Tylor Megill has recorded five or more strikeouts in each of his last four appearances against NL Central opponents that held a losing record.
• Juan Soto has recorded at least one hit in each of his last nine appearances against NL Central opponents that held a losing record.
• Pete Alonso ranks 2nd amongst qualified players for On Base Percentage (.473) this season.

New York Mets vs St. Louis Cardinals Prediction

The Mets are not only the better team, but Megill is coming off a hell of an April, where he allowed 20 hits and five earned runs in 26 innings. Megill is part of a Mets pitching staff that has been dealing all season long. The Cardinals are having issues finishing games, and Fedde has allowed 26 hits and 16 runs in his last 26.2 innings. The Cardinals have lost the last five games Fedde has pitched. Also, the Mets have owned Fedde throughout his career, which includes current hitters batting .330 with four homers in 112 at-bats. You can argue the price should be steeper than what it is. Give me the Mets on Saturday afternoon.

Randy Chambers's Pick: New York Mets -148