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New York Mets vs San Francisco Giants Prediction 4/5/2026 Today’s MLB Picks

Mar 31, 2026; St. Louis, Missouri, USA; New York Mets starting pitcher Kodai Senga (34) pitches against the St. Louis Cardinals during the fourth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

Mar 31, 2026; St. Louis, Missouri, USA; New York Mets starting pitcher Kodai Senga (34) pitches against the St. Louis Cardinals during the fourth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

MATCHUP New York Mets San Francisco Giants
Team Records 6-4 3-7
Where Oracle Park, San Francisco, California
When Sunday, April 5, 2026
Time 04:05 PM EDT
TV MLB.TV
The New York Mets and the San Francisco Giants meet Sunday in MLB action from Oracle Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New York Mets vs. San Francisco Giants prediction.

Starting Pitching Matchup

The New York Mets will send out Kodai Senga for the start here and Senga is 0-1 with a 3.00 ERA and 9 strikeouts this season. In his career, Senga is 1-0 with a 7.07 ERA and 11 strikeouts against the Giants. Logan Webb will start for San Francisco here and is 1-1 with a 7.36 ERA and 12 strikeouts this season. In his last five starts against the Mets, Webb is 2-1 with a 2.90 ERA and 30 strikeouts.

New York Mets Recap

The New York Mets come into this game looking to build on their 9-0 win over the Giants from Saturday’s matchup to sit at 5-4 this season. After this series, the Mets will head home for a game against the Arizona Diamondbacks.

Mets Win Back-To-Back Games

Going into Saturday’s game, Luis Robert Jr. has 7 hits including a home run and 6 RBIs while Juan Soto has a team-high 11 hits with 2 doubles, a home run and 5 RBIs. Brett Baty has 6 hits with a double, a triple and four RBIs while Francisco Lindor has 5 hits with a pair of triples as well. Marcus Semien also has 6 hits with a double and five RBIs as well this season. Bo Bichette also has 7 hits with 2 doubles and 5 RBIs as well this season.

San Francisco Giants Recap

The San Francisco Giants come into this game looking to shake off their loss to the Mets from Saturday’s matchup to sit at 3-6 this season. After this series, the will take on the Philadelphia Phillies at home.

Giants Drop Back-To-Back Games 

Entering Saturday, Luis Arraez has a team-high 10 hits with a double, a triple and 3 RBIs while Willy Adames has 7 hits with 2 doubles, a home run and 3 RBIs. Matt Chapman and Harrison Bader each have a home run and 3 RBIs while Jung Hoo Lee has 4 hits with 3 doubles and a team-high 4 RBIs. Heliot Ramos has 7 hits with a double and 2 RBIs but also has a team-high 12 strikeouts this season as well as the aforementioned Adames.

New York Mets @ San Francisco Giants Betting Trends: April 5, 2026


Why the San Francisco Giants will win


Why the New York Mets will win

Total Runs Facts

San Francisco Giants Player Prop Facts

New York Mets Player Prop Facts

Matchup/League Facts

New York Mets vs. San Francisco Giants Prediction

I’m looking at the Mets here. I get the case to be made for the Giants at home as they have Logan Webb on the bump, who is supposed to be the staff ace. However, the Mets have looked like far and away the better team here in this series, and I think the Mets pick up another win here. We’ve seen Webb look human at times already this year and I think Senga’s a solid option for the Mets that just didn’t get run support in his debut. I’ll look for that to change here as the Mets grab the win.

Chris Ruffolo's Pick: NY Mets +105

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