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Nationals vs Cardinals Prediction 07/10/2025 Picks

Jul 9, 2025; St. Louis, Missouri, USA;  St. Louis Cardinals relief pitcher Matt Svanson (49) pitches against the Washington Nationals during the eighth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

Jul 9, 2025; St. Louis, Missouri, USA; St. Louis Cardinals relief pitcher Matt Svanson (49) pitches against the Washington Nationals during the eighth inning at Busch Stadium. Mandatory Credit: Jeff Curry-Imagn Images

Washington (38-54) vs St. Louis (49-44)

July 10, 2025 at 07:45 PM EDT

The Line: Betting Odds: St. Louis -1.5 — Over/Under: +8.5

(Get latest betting odds)

In this article we will formulate a Nationals vs Cardinals prediction for this MLB game on Thursday, July 10th at Busch Stadium in St. Louis, Missouri. Let’s take a look at the prediction for this MLB matchup. 

Washington Nationals Betting Preview
The Washington Nationals are 38-54 this year after they split the first two games in this series by scores of 2-4 and 8-2. In their game two win, Washington jumped out to a 3-0 lead in the top of the first inning and they pulled away in the middle innings for the victory. The Nationals recorded nine hits in the game and they were led by Lowe, who went 2-4 with one home run and three RBIs in the win. Washington started Gore, who allowed five hits and one earned run over 6.0 innings for the win, while Henry allowed one earned run in relief. 

Prior to this series, the Nationals lost all three against the Red Sox, but did win two out of three against the Tigers before that. Washington has lost four of their last five games and they are currently last in the NL East standings. The Washington pitching staff has a 5.12 ERA with a 1.40 WHIP and a .263 opponent batting average, while the offense has scored 407 runs with a .247 batting average and a .313 on base percentage this season. James Wood has led Washington with 24 home runs and 69 RBIs, while Nathaniel Lowe has added 14 home runs and 61 RBIs this year. The projected starting pitcher for Washington is Michael Soroka, who is 3-6 with a 5.40 ERA and a 1.14 WHIP over 63.1 innings pitched this year. 

St. Louis Cardinals Betting Preview
The St. Louis Cardinals are 49-44 this season after they lost game two by a score of 8-2 on Wednesday night. St. Louis cut the deficit to 3-1 in the first inning, but they allowed the next five runs in the blowout loss. The Cardinals recorded seven hits in the game and they were led by Winn and Burleson, who both had one RBI in the loss. St. Louis started Pallante, who allowed eight hits and seven earned runs over 6.0 innings for the loss, while King allowed one earned run in relief. 

Prior to this series, the Cardinals lost two out of three against the Cubs and all three against the Pirates. St. Louis has lost six of their last eight games and they are currently third in the NL Central standings. The St. Louis pitching staff has a 4.10 ERA with a 1.27 WHIP and a .252 opponent batting average, while their offense has scored 420 runs with a .251 batting average and a .321 on base percentage this season. Wilson Contreras has led St. Louis with 11 home runs, 51 RBIs, and four stolen bases, while Nolan Arenado has added 10 home runs and 41 RBIs this year. The projected starting pitcher for St. Louis is Miles Mikolas, who is 4-6 with a 5.26 ERA and a 1.34 WHIP over 87.1 innings pitched this season. 

Why the Cardinals will beat the Nationals
The Nationals have lost nine of their last 10 games following a win.
The Cardinals have won 10 of their last 12 home games against National League opponents following a loss.
The Cardinals have covered the run line in nine of their last 10 games against NL East opponents.
The Nationals have failed to cover the run line in each of their last four games as road underdogs against NL Central opponents following a win.
The Cardinals have led after 3 innings in eight of their last 10 games as favorites.
The Nationals have trailed after 5 innings in four of their last five games.

Why the Nationals will beat the Cardinals
The Cardinals have lost each of their last nine Thursday night games at Busch Stadium.
The road team has won four of the Nationals’ last five games.
The Cardinals have failed to cover the run line in each of their last eight Thursday night games as favorites against National League opponents.
The Nationals have covered the run line in seven of their last eight night games against teams that held a winning record.
The Nationals have led after 3 innings in three of their last four night games.
The Nationals have led after 5 innings in three of their last four night games.

Total Runs Facts
Ten of the Nationals’ last 11 games have gone OVER the total runs line.
Eight of the last 10 games between the Nationals and Cardinals at Busch Stadium have gone OVER the total runs line.
The ‘Inning 1 UNDER 0.5 runs’ market has hit in six of the Nationals’ last seven night games at Busch Stadium.
The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Cardinals’ last five games.

St. Louis Cardinals Player Prop Facts
Miles Mikolas has recorded four or more strikeouts in each of his last four appearances.
Lars Nootbaar has hit a home run in three of his last four home appearances.
Willson Contreras has recorded at least one hit in each of his last 11 home appearances against NL East opponents that held a losing record.

Washington Nationals Player Prop Facts
Amed Rosario has hit a home run in three of his last five appearances in night games against NL Central teams that held a winning record.
Josh Bell has recorded a Double in each of the Nationals’ last three games as underdogs against NL Central opponents.
CJ Abrams has recorded at least one hit in each of the Nationals’ last eight night games against opponents that held a winning record.

Nationals vs Cardinals Prediction
Washington was able to pick up a badly needed win on Wednesday night, but they have really struggled on the mound, as they have allowed 33 runs in their last five games. The Nationals are 20-26 on the road this year, while the Cardinals are 27-18 at home. St. Louis is another team that has struggled over the last two weeks, as their offense has been very inconsistent. The Cardinals are starting Mikolas, who has allowed 14 earned runs in his last 10.0 innings. The Nationals are going with Soroka, who has allowed 7, 1, 3, 3, and 4 earned runs in his last five. Take the over here. 

David Racey's Pick: Over 8.5

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