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Minnesota Twins vs Washington Nationals Prediction 07/27/2025 Picks

Jul 26, 2025; Minneapolis, Minnesota, USA; Washington Nationals first baseman Nathaniel Lowe (33) connects with the ball in the first inning. Minnesota Twins shortstop Carlos Correa (4) would field the ball and throw him out at first at Target Field. Mandatory Credit: Matt Blewett-Imagn Images

Jul 26, 2025; Minneapolis, Minnesota, USA; Washington Nationals first baseman Nathaniel Lowe (33) connects with the ball in the first inning. Minnesota Twins shortstop Carlos Correa (4) would field the ball and throw him out at first at Target Field. Mandatory Credit: Matt Blewett-Imagn Images

Washington (42-62) vs Minnesota (50-54)

July 27, 2025 at 02:10 PM EDT

The Line: Betting Odds: Minnesota -185 / Washington +155 — Over/Under: +9.5

(Get latest betting odds)

In this article, we will formulate a Washington Nationals vs Minnesota Twins Prediction for this MLB game on Sunday, July 27th at the Target Field in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Minnesota Twins Preview

The Minnesota Twins have a 50-54 record this season and are sitting in 4th place in the AL Central. The Twins have a 29-21 home record and are 43-54 in over/under. They are coming off a 3-9 home defeat by the Nationals, and are 4-5 in their last 9 games. Under is 6-3 in their last 9 games, and they are playing the Red Sox and the Guardians next.

The Twins have a .242 batting average this season, a .313 OBP, and a.400 Slugging percentage. Minnesota’s pitching staff has a 4.17 ERA and 1.25 WHIP. Byron Buxton leads the Twins with 92 hits, adding a team-high 59 RBI, 23 home runs, and he is the team’s best hitter with a .282 batting average.

The Twins have not yet announced a starting pitcher for this game.

Washington Nationals Preview

The Washington Nationals have a 42-62 record this season and are sitting on the last place of the NL East. The Nationals have a 21-31 road record and are 54-46 in over/under. They are coming off a 9-3 road victory over the Twins, which snapped their previous two-game losing streak. Under is 3-1 in their last 4 games, and are playing the Astros and the Brewers next.

The Nationals have a .244 batting average this season, .310 OBP and .389 Slugging percentage. Washington’s pitching staff has a 5.14 ERA and 1.41 WHIP. James Wood leads the Nationals with 103 hits, adding 70 RBI and a team-high 24 home runs. CJ Abrams is the team’s best hitter with a .271 batting average.

Jake Irvin (R) will take the mound for the Nationals, and he has a 7-5 record, 4.81 ERA and 1.33 WHIP.

Why the Minnesota Twins will win

  • The Nationals have lost each of their last eight day games following a win.
  • The Twins have won each of their last five games at Target Field following a loss.
  • The Nationals have failed to cover the run line each of their last eight day games against teams that held a losing record.
  • The Twins have covered the run line in three of their last four home games following a home loss.
  • The Nationals have lost the first inning in four of their last five day games against American League opponents.
  • The Nationals have trailed after 3 innings in each of their last seven day games against American League opponents.
  • The Nationals have trailed after 5 innings in each of their last eight day games.

Why the Washington Nationals will win

  • The Twins have lost four of their last five games as favorites against National League opponents following a home loss.
  • The Nationals have won three of their last four games as underdogs after playing the previous day.
  • The Twins have failed to cover the run line in each of their last eight games as favorites against NL East opponents.
  • The Nationals have covered the run line in seven of their last eight road games against American League opponents after playing the previous day.
  • The Nationals have won the first inning in four of their last five day games against the Twins.
  • The Twins have trailed after 3 innings in four of their last five games at Target Field against NL East opponents that held a losing record.
  • The Nationals have led after 5 innings in three of their last four games against AL Central opponents.

Total Runs Facts

  • Ten of the Nationals’ last 11 games against American League opponents have gone OVER the total runs line.
  • Six of the Twins’ last seven games as favorites against NL East opponents have gone UNDER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Twins’ last six home games.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Nationals’ last five road games.

Matchup/League Facts

  • The Twins rank 1st in the league for walks allowed this season (268).
  • The Twins rank T25th in the league for steals this season (53).
  • The Nationals rank 28th in the league for ERA this season (5.14).
  • The Nationals rank 28th in the league for opponent batting average this season (.264).

Washington Nationals vs Minnesota Twins Prediction

The Twins are 3-1 in their last 4 meetings against the Nats, but the Nationals are 5-2 in their last 7 visits in Minnesota. Under is 5-3 in their last 8 meetings in Minnesota.  

In this Washington Nationals vs Minnesota Twins Prediction, the Twins are coming as -185 home favorites. The Twins are rightfully favored, as they have a better overall record, and have been very strong at home, while the Nats are struggling on the road. Irvin has been weaker on the road for the Nationals, with a 5.34 road ERA, and has been in terrible form lately, with a 7.20 ERA across his last five starts. The Nationals also have the worst bullpen in the league, but I cannot back Minnesota as big home favorites without knowing their starting pitcher. David Festa is a possibility, and if he starts, he has a 5.40 ERA and 1.28 WHIP this season. So with two struggling pitchers, and the worst bullpen in the league, I expect a high-scoring game, so take the over 9.5 runs in this one.

Nikos Lagouretos's Pick: Over 9.5

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