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Minnesota Twins vs Philadelphia Phillies Prediction 9/28/2025 Today’s MLB Picks

Aug 8, 2025; Arlington, Texas, USA;  Philadelphia Phillies starting pitcher Cristopher Sanchez (61) throws during the fifth inning against the Texas Rangers at Globe Life Field. Mandatory Credit: Kevin Jairaj-Imagn Images

Aug 8, 2025; Arlington, Texas, USA; Philadelphia Phillies starting pitcher Cristopher Sanchez (61) throws during the fifth inning against the Texas Rangers at Globe Life Field. Mandatory Credit: Kevin Jairaj-Imagn Images

MATCHUP Minnesota Twins Philadelphia Phillies
Team Records 70-92 96-66
Where Citizens Bank Park, Philadelphia, Pennsylvania
When Sunday, September 28, 2025
Time 03:05 PM EDT
TV MLB.TV

In this article, we will formulate a Twins vs Phillies Prediction for this MLB game on Sunday, September 28th at the Citizens Bank Park in the third game of this series, with both teams being tied 1-1 wins. Let’s take a look at the prediction for this MLB matchup.

Philadelphia Phillies Preview

The Philadelphia Phillies have a 96-66 record this season and are sitting on the first place of the NL East. They have a 54-26 home record, and are 72-79 in over/under. They are coming off a 0-5 home defeat by the Twins, that ended their three-game winning streak. Their last three games have gone under the total.

The Phillies have a .259 batting average this season, .329 OBP and .432 Slugging percentage. Philly’s pitching staff has a 3.81 ERA and 1.24 WHIP. Trea Turner leads the Phillies with 179 hits and he is the team’s best hitter, with a .305 batting average. Kyle Schwarber leads the team with 132 RBI and a team-high 56 home runs.

Cristopher Sanchez (L) is the projected starting pitcher for the Phillies, and he has a 13-5 record, 2.57 ERA and 1.08 WHIP.

Minnesota Twins Preview

The Minnesota Twins have a 70-91 record this season and are sitting on the 4th place of the AL Central. The Twins have a 32-48 road record and are 73-78 in over/under. They are coming off a 5-0 road victory over the Phillies and their last 8 games have gone under the total.

The Twins have a .239 batting average this season, .311 OBP and .398 Slugging percentage. Minnesota’s pitching staff has a 4.57 ERA and 1.32 WHIP. Byron Buxton leads the Twins with 129 hits, adding team-highs both in RBI, with 83, and in home runs, with 35. He is also the team’s best hitter with a .264 batting average.

Simeon Woods Richardson (R) is the projected starter for the Twins, and he has a 7-4 record, 4.27 ERA and 1.34 WHIP.

Minnesota Twins @ Philadelphia Phillies Betting Trends: September 28, 2025

Why the Philadelphia Phillies will win

Why the Minnesota Twins will win

Total Runs Facts

Philadelphia Phillies Player Prop Facts

Minnesota Twins Player Prop Facts

Matchup/League Facts

Twins vs Phillies Prediction

The Twins are 5-2 in their last 7 head-to-head meetings against the Phillies, and they are 4-3 in their last 7 meetings in Philly.

In this Twins vs Phillies Prediction, the Phillies are coming as -210 home favorites. Sanchez has been elite for the Phillies this season, and he has been even better at home, with a 2.05 ERA. He is coming into this matchup in excellent form, with a 4-1 record and 1.85 ERA across his last 5 starts. On the flip side, Richardson has been terrible on the road for the Twins, with a 5.89 ERA. Philly has both a better bullpen, and a better offense, that is even stronger against right-handed pitching. Take the Phillies to win this one comfortably and cover the runline.

Nikos Lagouretos's Pick: Philadelphia Phillies -1.5

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