Minnesota Twins vs Los Angeles Angels Prediction 9/8/2025 Today’s MLB Picks

In this article, we will formulate a Twins vs Angels Prediction for this MLB game on Monday, September 8th at the Angel Stadium in the opening game of this series. Let’s take a look at the prediction for this MLB matchup.

Los Angeles Angels Preview

The Los Angeles Angels have a 67-76 record this season and are sitting on the 4th place of the AL West. The Angels have a 35-37 home record and 77-63 in over/under They are coming off a 4-3 home victory over the A’s, that ended their three-game losing streak. Under is 7-3 in their last 10 games and are playing the Mariners and the Brewers next.

The Angels have a .228 batting average this season, .303 OBP and .400 Slugging percentage. LA’s pitching staff has a 4.81 ERA and 1.43 WHIP. Zach Neto leads the Angels with 125 hits, while Nolan Schanuel is the team’s best hitter with a .266 batting average. Taylor Ward leads the team with 95 RBI, while Jo Adell adds a team-high 35 home runs.

Caden Dana (R) is the projected starting pitcher for the Angels, and he has a 0-0 record,  4.91 ERA and 1.36 WHIP.

Minnesota Twins Preview

The Minnesota Twins have a 63-80 record this season and are sitting on the 4th place of the AL Central. The Twins have a 28-44 road record and are 67-67 in over/under. They are coming off a 5-1 road victory over the Royals, that ended their six-game losing streak. Over is 7-3 in their last 10 games and are playing the Yankees and the Diamondbacks next.

The Twins have a .239 batting average this season, .312 OBP and .397 Slugging percentage. Minnesota’s pitching staff has a 4.56 ERA and 1.33 WHIP. Trevor Larnach leads the Twins with 116 hits, while Byron Buxton adds team-highs both in RBI, with 74, and in home runs, with 30. He is also the team’s best hitter with a .271 batting average.

Simeon Woods Richardson (R) is the projected starter for the Twins, and he has a 5-4 record, 4.53 ERA and 1.40 WHIP.

Minnesota Twins @ Los Angeles Angels Betting Trends: September 8, 2025

• Probable Starting Pitcher: Caden Dana      Record this season: 0-0      ERA: 4.91
• Home Record: 0-0
• Last 5 against Twins: –

Why the Los Angeles Angels will win

• The Twins have lost each of their last eight games following a win.
• The Angels have won each of their last eight Monday night games against American League opponents.
• The Twins have failed to cover the run line each of their last six games against teams that held a losing record.
• The Angels have covered the run line in each of their last eight Monday night games against American League opponents.
• The Twins have trailed after 3 innings in nine of their last 10 road night games.
• The Twins have trailed after 5 innings in five of their last six road night games.
• The Angels have won the first inning in three of their last four games.

• Probable Starting Pitcher: Simeon Woods-Richardson      Record this season: 5-4      ERA: 4.53
• Road Record: 1-2
• Last 5 against Angels: 1-0

Why the Minnesota Twins will win

• The Angels have lost each of their last four games as favorites against American League opponents.
• The underdogs have won six of the Twins’ last seven games.
• The Twins have covered the run line in each of their last eight games as road underdogs against AL West opponents.
• The Angels have failed to cover the run line each of their last six night games against teams that held a losing record.
• The Angels have lost the first inning in four of their last five night games against opponents that held a losing record.
• The Angels have trailed after 3 innings in each of their last six games against AL Central opponents that held a losing record.
• The Angels have trailed after 5 innings in each of their last six games against AL Central opponents that held a losing record.

Total Runs Facts

• Each of the Angels’ last four games as favorites against American League opponents have gone OVER the total runs line.
• Five of the Twins’ last six night games as underdogs have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Twins’ last nine games against AL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Angels’ last four games.

Los Angeles Angels Player Prop Facts

• Zach Neto has recorded at least one Double in three of the Angels’ last four games as favorites against the Twins.
• Jo Adell has hit a home run in four of the Angels’ last five games against opponents that held a losing record.
• Zach Neto has recorded at least one hit in each of the Angels’ last 15 Monday games.
• Jo Adell ranks 8th in the league in Home Runs (35) this season.

Minnesota Twins Player Prop Facts

• Trevor Larnach has recorded at least one hit in each of his last seven appearances against the Angels.
• Ryan Jeffers has hit a home run in three of his last five road appearances against AL West opponents that held a losing record.
• Byron Buxton ranks 5th amongst qualified players for Slugging Percentage (.562) this season.

Matchup/League Facts

• The Angels rank 30th in the league for strikeouts against this season (1409).
• The Angels rank 30th in the league for walks allowed this season (547).
• The Twins rank 4th in the league for walks allowed this season (405).
• The Twins rank 26th in the league for opponent batting average this season (.259).

Twins vs Angels Prediction

The Twins are 9-1 in their last 10 head-to-head meetings against the Angels, and have won their last 3 visits in Los Angeles. Over is 6-3-1 in their last 10 meetings.

In this Twins vs Angels Prediction, the Angels are coming as -125 home favorites. I don’t trust either pitcher in this matchup, as we have not seen enough of Dana for the Angels, and Richardson has been bad for the Twins, especially on the road, where he has a 5.95 ERA. Both teams also have bad bullpens to follow those pitchers, and they are allowing runs like crazy lately. The Angels have allowed 30 runs in three games in the series versus the A’s, while the Twins have allowed 11+ runs in three of their last six games. I anticipate another high-scoring affair, so take the over 9.5 runs in this one.