Minnesota Twins vs Kansas City Royals Prediction 9/6/2025 Today’s MLB Picks

In this article, we will formulate a Twins vs Royals Prediction for this MLB game on Saturday, September 6th at the Kauffman Stadium in the second game of this series, with the Royals having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Kansas City Royals Preview

The Kansas City Royals have a 72-69 record this season and are sitting on the second place of the AL Central. The Royals have a 39-34 home record and are 59-81 in over/under. They are coming off a 2-1 home victory over the Twins, and have back-to-back wins. Under is 7-0 in their last 7 games and are playing the Phillies and the Guardians next.

The Royals have a .244 batting average this season, .305 OBP and .393 Slugging percentage. Kansas’ pitching staff has a 3.64 ERA and 1.24 WHIP. Bobby Witt Jr. leads the Royals with 160 hits, while Maikel Garcia is the team’s best hitter with a .294 batting average. Vinnie Pasquantino leads the team in RBI, with 96, and a team-high 29 home runs.

Stephen Kolek (R) is the projected starter for the Royals, and he has a 13-7 record, 3.08 ERA and 0.97 WHIP.

Minnesota Twins Preview

The Minnesota Twins have a 62-79 record this season and are sitting on the 4th place of the AL Central. The Twins have a 27-43 road record and are 66-66 in over/under. They are coming off a 1-2 road defeat by the Royals, and are 1-6 in their last 7 games. Over is 12-3 in their last 15 games and are playing the Angels and the Diamondbacks next.

The Twins have a .239 batting average this season, .312 OBP and .397 Slugging percentage. Minnesota’s pitching staff has a 4.53 ERA and 1.32 WHIP. Trevor Larnach leads the Twins with 116 hits, while Byron Buxton adds team-highs both in RBI, with 72, and in home runs, with 29. He is also the team’s best hitter with a .271 batting average.

Joe Ryan (R) is the projected starter for the Twins, and he has a 4-5 record, 3.99 ERA and 1.26 WHIP.

Why the Kansas City Royals will win

• The Twins have lost each of their last six games as favorites against AL Central opponents.
• The Royals have won 23 of their last 25 home games against AL Central opponents that held a losing record.
• The Twins have failed to cover the run line in each of their last six games as favorites against AL Central opponents.
• The underdogs have covered the run line in each of the Twins’ last five games.
• The Twins have trailed after 3 innings in each of their last six games as road favorites against American League opponents.
• The Twins have trailed after 5 innings in five of their last six road games.
• The Twins have lost the first inning in three of their last four games as road favorites against AL Central opponents.

Why the Minnesota Twins will win

• The Royals have lost each of their last seven games as underdogs against AL Central opponents following a win.
• The favorites have won each of the Twins’ last six games at Kauffman Stadium.
• The Royals have failed to cover the run line in each of their last seven games as underdogs against AL Central opponents following a win.
• The road team has covered the run line in seven of the Royals’ last eight games.
• The Twins have won the first inning in four of their last five road games against AL Central opponents that held a winning record.
• The Royals have trailed after 5 innings in six of their last seven games as home underdogs.

Total Runs Facts

• Each of the last eight games between the Twins and Royals at Kauffman Stadium have gone UNDER the total runs line.
• Nine of the Twins’ last 11 games have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Royals’ last five games as underdogs.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in five of the Twins’ last six night games at Kauffman Stadium.

Matchup/League Facts

• The Royals rank 1st in the league for strikeouts against this season (954).
• The Royals rank 29th in the league for walks this season (369).
• The Twins rank 3rd in the league for walks allowed this season (394).
• The Twins rank 26th in the league for hits allowed this season (1244).

Twins vs Royals Prediction

Both teams are tied 5-5 wins in their last 10 head-to-head meetings, but the Royals are 4-1 in their last 5 meetings in Kansas City. Under is 9-2 in their last 11 meetings.

In this Twins vs Royals Prediction, the Twins are coming as -125 road favorites. The Twins look like they have given up on the season, so taking them as road favorites is out of the question, even with Ryan on the mound, who has 11 earned runs in his last three starts. Kolek had a quality start in his first start with the Royals, and Kansas City has a superior bullpen to back him up. I like the hosts as home dogs in this one, so take the Kansas City Royals and the plus money in this one.