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Minnesota Twins vs Cleveland Guardians Prediction 7/23/2026 Today’s MLB Picks

Jul 22, 2026; Cleveland, Ohio, USA; Cleveland Guardians left fielder Steven Kwan (38) catches a fly ball in the fifth inning against the Minnesota Twins at Progressive Field. Mandatory Credit: David Richard-Imagn Images

Jul 22, 2026; Cleveland, Ohio, USA; Cleveland Guardians left fielder Steven Kwan (38) catches a fly ball in the fifth inning against the Minnesota Twins at Progressive Field. Mandatory Credit: David Richard-Imagn Images

MATCHUP Minnesota Twins Cleveland Guardians
Team Records 50-53 54-49
Spread +1.5 -188 -1.5 154
Moneyline +117 -141
Total Over 7.5 (-118) Under 7.5 (-102)
Where Progressive Field, Cleveland, Ohio
When Thursday, July 23, 2026
Time 01:10 PM EDT
TV ESPN Unlmtd
The Minnesota Twins and Cleveland Guardians meet Thursday in MLB action at Progressive Field. Here’s a Minnesota Twins vs Cleveland Guardians Prediction. This article will include a Minnesota Twins vs Cleveland Guardians Pick.

Minnesota Twins Betting Preview


The Minnesota Twins are 50-53 on the year and play the Athletics and Royals next. The Minnesota Twins are batting .248 on the season and have a .321 OBP and a .413 slugging percentage. The Minnesota Twins’ pitching staff has a 4.77 ERA and a 1.40 WHIP. Josh Bell leads the Minnesota Twins with 92 hits and 62 RBI, while Byron Buxton and Brooks Lee have combined for 178 hits and 101 RBI.

Taj Bradley gets the ball for the Minnesota Twins, and he is 9-4 with a 3.85 ERA and 124 strikeouts this season. Bradley is 2-1 with a 1.54 ERA and 31 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview


The Cleveland Guardians are 54-49 on the year and play the Rays and Reds next. The Cleveland Guardians are batting .234 on the season, have a .313 OBP, and have a .378 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.74 ERA and a 1.27 WHIP. Brayan Rocchio leads the Cleveland Guardians with 95 hits and 48 RBI, while Chase DeLauter and Steven Kwan have combined for 171 hits and 68 RBI.

Gavin Williams gets the ball for the Cleveland Guardians, and he is 10-5 with a 4.00 ERA and 145 strikeouts this season. Williams is 4-3 with a 3.27 ERA and 47 strikeouts in his career against the Minnesota Twins.

Why the Cleveland Guardians will win

Why the Minnesota Twins will win

Total Runs Facts

Cleveland Guardians Player Prop Facts

Minnesota Twins Player Prop Facts

Matchup/League Facts

Minnesota Twins vs Cleveland Guardians Prediction


Bradley has been solid this season, but his numbers do jump to a 4.50 ERA and a .245 allowed batting average in 56 innings on the road. The Twins have also had issues stringing wins together as of late. The Guardians are the better side, and while Williams is having a rough July, he has a 3.45 ERA and .230 allowed batting average in 60 innings at home. Quick turnaround; I trust the Guardians at home in this spot.

Randy Chambers's Pick: Cleveland Guardians

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