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Minnesota Twins vs Cleveland Guardians Prediction 08/03/2025 Today’s MLB Picks

Aug 2, 2025; Cleveland, Ohio, USA; Cleveland Guardians third baseman Jose Ramirez (11) stands on deck in the third inning against the Minnesota Twins at Progressive Field. Mandatory Credit: David Richard-Imagn Images

Aug 2, 2025; Cleveland, Ohio, USA; Cleveland Guardians third baseman Jose Ramirez (11) stands on deck in the third inning against the Minnesota Twins at Progressive Field. Mandatory Credit: David Richard-Imagn Images

Minnesota (51-59) vs Cleveland (56-54)

August 3, 2025 at 01:40 PM EDT

The Line: Betting Odds: Cleveland -1.5 — Over/Under: +8

(Get latest betting odds)

The Minnesota Twins and Cleveland Guardians meet Sunday in MLB action at Progressive Field. Here’s a Minnesota Twins vs Cleveland Guardians Prediction. This article will include a Minnesota Twins vs Cleveland Guardians Pick.

Minnesota Twins Betting Preview

The Minnesota Twins are 51-59 on the year and play the Tigers, Royals, and Yankees next. The Minnesota Twins are batting .241 on the season, have a .312 OBP, and a .397 slugging percentage. The Minnesota Twins pitching staff has a 4.28 ERA and a 1.27 WHIP. Byron Buxton leads the Minnesota Twins with 92 hits and 59 RBI, while Trevor Larnach and Brooks Lee have combined for 156 hits and 87 RBI. 

Jose Urena gets the ball for the Minnesota Twins, and he is 0-0 with a 5.40 ERA and 10 strikeouts this season. Urena is 0-1 with a 3.95 ERA and 11 strikeouts in his career against the Cleveland Guardians.

Cleveland Guardians Betting Preview

The Cleveland Guardians are 56-54 on the year and play the Mets, White Sox, and Marlins next. The Cleveland Guardians are batting .228 on the season, have a .301 OBP, and a .377 slugging percentage. The Cleveland Guardians’ pitching staff has a 3.86 ERA and a 1.30 WHIP. Jose Ramirez leads the Cleveland Guardians with 121 hits and 59 RBI while Steven Kwan and Carlos Santana have combined for 200 hits and 84 RBI.

Joey Cantillo gets the ball for the Cleveland Guardians, and he is 2-1 with a 4.14 ERA and 63 strikeouts this season. Cantillo is 0-1 with a 2.77 ERA and 13 strikeouts in his career against the Minnesota Twins.

Why the Cleveland Guardians will win

  • The Guardians have won 13 of their last 14 day games against the Twins following a win.
  • The Twins have lost eight of their last nine road games against American League opponents that held a winning record.
  • The Twins have failed to cover the run line in six of their last seven day games against AL Central opponents that held a winning record.
  • The Guardians have covered the run line in seven of their last eight Sunday games as home favorites against American League opponents.
  • The Guardians have led after 5 innings in each of their last five Sunday day games as home favorites.
  • The Twins have trailed after 3 innings in each of their last four games against American League opponents.

Why the Minnesota Twins will win

  • The Twins have won three of their last four games following a road loss.
  • The underdogs have covered the run line in each of the Twins’ last 10 games at Progressive Field.
  • The Guardians have failed to cover the run line in each of their last five games against AL Central opponents following a win.

Cleveland Guardians Player Prop Facts

  • Jose Ramirez has hit a home run in four of the Guardians’ last seven games as home favorites against AL opponents.
  • Jose Ramirez has recorded at least one hit in each of the Guardians’ last nine games against AL opponents.
  • Jose Ramirez is one of only six players to hit over .300 and have 45+ RBIs this season.

Minnesota Twins Player Prop Facts

  • Trevor Larnach has recorded at least one hit in each of his last nine Sunday day appearances with the Twins as underdogs.
  • Byron Buxton has hit at least one home run in six of his last nine road appearances against opponents that held a winning record.

Minnesota Twins vs Cleveland Guardians Prediction

The Twins look like a team that’s giving up on the season, and Urena just doesn’t inspire much confidence. Urena has always been a journeyman with questionable control, and he’s allowed 23 hits and 11 runs in 18.1 innings this season. Cantillo has had his issues as well, but he’s pitching for a hot Guardians team that’s shining the bats well and looks to finish the week strong. Two teams heading in different directions. I like the Guardians for a fifth straight victory. 

Randy Chambers's Pick: Cleveland Guardians

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