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Minnesota Twins vs Chicago White Sox Prediction 5/28/2026 Today’s MLB Picks

May 27, 2026; Chicago, Illinois, USA;  Chicago White Sox second baseman Chase Meidroth (10) is dunked by left fielder Sam Antonacci (10) left, and shortstop Colson Montgomery (12) after the game against the Minnesota Twins at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

May 27, 2026; Chicago, Illinois, USA; Chicago White Sox second baseman Chase Meidroth (10) is dunked by left fielder Sam Antonacci (10) left, and shortstop Colson Montgomery (12) after the game against the Minnesota Twins at Rate Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Minnesota Twins Chicago White Sox
Team Records 27-29 28-27
Spread +1.5 -186 -1.5 153
Moneyline +118 -142
Total Over 8 (-105) Under 8 (-115)
Where Rate Field, Chicago, Illinois
When Thursday, May 28, 2026
Time 02:10 PM EDT
TV MLB.TV
The Minnesota Twins and Chicago White Sox meet on Thursday in MLB action at Comerica Park. Here’s a Minnesota Twins vs Chicago White Sox Prediction. This article will include a Minnesota Twins vs Chicago White Sox Pick.

Minnesota Twins Betting Preview


The Minnesota Twins are 27-29 on the year and play the White Sox and Pirates next. The Minnesota Twins are batting .236 on the season and have a .319 OBP and a .385 slugging percentage. The Minnesota Twins’ pitching staff has a 4.33 ERA and a 1.33 WHIP. Byron Buxton leads the Minnesota Twins with 51 hits and 27 RBI, while Luke Keaschall and Brooks Lee have combined for 92 hits and 48 RBI.

Kendry Rojas gets the ball for the Minnesota Twins, and he is 1-0 with a 1.26 ERA and 14 strikeouts this season. This will be Rojas’ first career game against the Chicago White Sox.

Chicago White Sox Betting Preview


The Chicago White Sox are 28-27 on the year and play the Twins and Tigers next. The Chicago White Sox are batting .236 on the season, have a .325 OBP, and have a .403 slugging percentage. The Chicago White Sox pitching staff has a 4.40 ERA and a 1.33 WHIP. Chase Meidroth leads the Chicago White Sox with 54 hits and 18 RBI, while Munetaka Murakami and Miguel Vargas have combined for 92 hits and 71 RBI.

Davis Martin gets the ball for the Chicago White Sox, and he is 7-1 with a 2.04 ERA and 66 strikeouts this season. Martin is 2-3 with a 6.15 ERA and 21 strikeouts in his career against the Minnesota Twins.

Why the Chicago White Sox will win

Why the Minnesota Twins will win

Total Runs Facts

Chicago White Sox Player Prop Facts

Minnesota Twins Player Prop Facts

Minnesota Twins vs Chicago White Sox Prediction


Quick turnaround and a lot of offense yesterday, it feels like things calm down here. Rojas has pitched just 14.1 innings in his big league career, but he has a 1.26 ERA and 1.47 WHIP. Martin has a 2.04 ERA and 1.02 WHIP through 61.2 innings. Martin has allowed 19 hits and 6 runs in his last 24.2 innings. In 23.2 home innings, Martin has a 1.14 ERA and a .216 allowed batting average. Two pitchers in fantastic form. Give me the under in this spot.

Randy Chambers's Pick: Under 8

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