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Milwaukee Brewers vs San Diego Padres Prediction 10/7/2026 Today’s MLB Picks

Sep 26, 2026; San Diego, California, USA;  San Diego Padres starting pitcher Walker Buehler (10) throws a pitch during the first inning against the Arizona Diamondbacks at Petco Park.  Mandatory Credit: David Frerker-Imagn Images

Sep 26, 2026; San Diego, California, USA; San Diego Padres starting pitcher Walker Buehler (10) throws a pitch during the first inning against the Arizona Diamondbacks at Petco Park. Mandatory Credit: David Frerker-Imagn Images

MATCHUP Milwaukee Brewers San Diego Padres
Team Records 103-59 91-71
Spread -1.5 167 +1.5 -205
Moneyline -105 -115
Total Over 7.5 (-105) Under 7.5 (-115)
Where Petco Park, San Diego, California
When Wednesday, October 7, 2026
Time 10:00 PM EDT
TV FS1
In this article, we will formulate a Brewers vs Padres Prediction for this MLB matchup on Wednesday, October 7th in Game 4 of this NLDS matchup. Let’s take a look at the prediction for this MLB matchup.

San Diego Padres Preview


The San Diego Padres have a 91-71 record this season and finished in the 2nd place of the NL West. They have a 51-30 home record and are coming off a 4-3 home win against the Brewers.

The San Diego Padres have a .265 batting average this postseason, .338 OBP and .386 Slugging percentage. San Diego’s pitching staff has a 1.82 ERA and 1.01 WHIP. Ty France is the team’s best hitter with a .467 batting average. Manny Machado leads the team in RBI with 2, adding a team-high one home run.

Walker Buehler (R) is the projected starting pitcher for the Padres, and he has a 9-6 record, 4.63 ERA and 1.35 WHIP.

Milwaukee Brewers Preview


The Milwaukee Brewers have a 103-59 record this season and finished in the 1st place of the NL Central. They have a 48-33 road record and are coming off a 3-4 road loss against the Padres.

The Milwaukee Brewers have a .190 batting average this postseason, .301 OBP and .302 Slugging percentage. Milwaukee’s pitching staff has a 1.50 ERA and 1.28 WHIP. Christian Yelich is the team’s best hitter with a .333 batting average. Jackson Chourio leads the team in RBI with 4, while William Contreras adds a team-high one home run.

Robert Gasser (L) is the projected starting pitcher for the Brewers, and he has a 5-5 record, 3.87 ERA and 1.19 WHIP.

Milwaukee Brewers @ San Diego Padres Betting Trends: October 7, 2026


Why the San Diego Padres will win

Why the Milwaukee Brewers will win

Total Runs Facts

San Diego Padres Player Prop Facts

Milwaukee Brewers Player Prop Facts

Matchup/League Facts

Brewers vs Padres Prediction


The Padres are 7-3 in their last 10 meetings against the Brewers but have lost two of their last three visits in Milwaukee.

In this Brewers vs Padres Prediction, the Padres are coming as -113 home favorites. The Padres lived to fight another day yesterday and things will get trickier today as Walker Buehler takes the mound. He had just one earned run in his previous meeting against the Brewers this season and I don’t trust Gasser to close out a series for the Brewers on the road. The Padres have a better bullpen and have also been the best team against left-handed pitching in the last 30 days. Take the Padres in this one.

Nikos Lagouretos's Pick: San Diego Padres ML

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