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Milwaukee Brewers vs Pittsburgh Pirates Prediction 5/23/25 MLB Picks

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Pittsburgh Pirates (17-34) vs Milwaukee Brewers (25-26)

Game Info: Friday, May 23, 2025 at 6:40 pm (PNC Park)

The Line: Betting Odds: Pittsburgh Pirates -122 / Milwaukee Brewers +102 — Over/Under: 7

(Get latest betting odds)

The Milwaukee Brewers and the Pittsburgh Pirates meet Friday in MLB action from PNC Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Milwaukee Brewers vs. Pittsburgh Pirates prediction.

Starting Pitching Matchup

The Milwaukee Brewers will send out Freddy Peralta for the start here, and Peralta is 5-3 with a 2.59 ERA and 57 strikeouts this season. In his last five starts against the Pirates, Peralta is 5-3 with a 2.59 ERA and 57 strikeouts. Paul Skenes will get the start for the Pirates and is 3-5 with a 2.44 ERA and 62 strikeouts this season. This will be Skenes’ second career start against the Brewers.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this game looking to build on their 8-5 win over the Pirates from Thursday’s matchup to improve to 25-26 on the year. After this series, the Brewers will head home for an interleague series against the Boston Red Sox.

Brewers Win 4 Of Their Last 5

Brice Turang has 51 hits with 4 home runs, 20 RBIs, and 13 stolen bases, while Jackson Chourio has 53 hits with a team-high 15 doubles, 7 home runs, and 26 RBIs, and Sal Frelick has 46 hits as well as 3 triples and 9 stolen bases so far this season. Christian Yelich also has 8 stolen bases with 9 homers and 30 RBIs while also adding 4 doubles. Yelich also has a team-high 56 strikeouts up to this point in the year. William Contreras has 4 homers and 23 RBIs as well this season. Rhys Hoskins has added 45 hits with 7 home runs, 27 RBIs, and 9 doubles.

Why the Milwaukee Brewers will win

Milwaukee Brewers Player Prop Facts

Pittsburgh Pirates Recap

The Pittsburgh Pirates will be out to bounce back from their series-opening loss to the Brewers on Thursday, falling to 17-34 on the year as a result. After this series, the Pirates will head on the road for a series against the Arizona Diamondbacks.

Pirates Fall Flat In The Opener

Bryan Reynolds has 41 hits with 7 doubles, 6 home runs, and 25 RBIs while also leading the Pirates with 60 strikeouts so far this season. Oneil Cruz has posted a team-high 8 home runs and 19 RBIs with 18 stolen bases, while Isiah Kiner-Falefa has 37 hits with 7 stolen bases. Emmanuel Valdez also has a pair of triples this season. Tommy Pham has 4 doubles and Andrew McCutchen has 35 hits with 7 doubles, and KeBryan Hayes has 44 hits with 15 RBIs and 5 stolen bases.

Why the Pittsburgh Pirates will win

Pittsburgh Pirates Player Prop Facts

Total Runs Facts

Milwaukee Brewers vs. Pittsburgh Pirates Prediction

I’m on the under here. I get the case to be made for either side in this game, because this is a fantastic starting pitching option. However, these are also two teams that I’ve grown to not really trust as of late at the plate, and like I said, given the starting pitching matchup on both sides, I think we could have a bit of a pitcher’s duel here. Give me the under.

Chris Ruffolo's Pick: Under 7

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