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Milwaukee Brewers vs Cleveland Guardians Prediction 5/12/25 MLB Picks

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Cleveland Guardians (23-17) vs Milwaukee Brewers (20-21)

Game Info: Monday, May 12, 2025 at 6:10 pm (Progressive Field)

The Line: Betting Odds: Cleveland Guardians +114 / Milwaukee Brewers -135 — Over/Under: 8

(Get latest betting odds)

The Milwaukee Brewers and the Cleveland Guardians meet Monday in MLB action from Progressive Field. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Milwaukee Brewers vs. Cleveland Guardians prediction.

Starting Pitching Matchup

The Milwaukee Brewers will send out Freddy Peralta for the start here, and Peralta is 4-2 with a 2.18 ERA and 48 strikeouts this season. In his career, Peralta is 1-1 with a 3.27 ERA and 8 strikeouts against the Guardians. Ben Lively will get the nod for the Guardians here and is 2-2 with a 3.46 ERA and 28 strikeouts this season. In his last five starts against the Brewers, Lively is 0-4 with a 3.38 ERA and 21 strikeouts.

Milwaukee Brewers Recap

The Milwaukee Brewers come into this series looking to build on a 4-2 win over the Rays from Sunday’s series finale to avoid the sweep and sit at 20-21 on the year. After this series, the Brewers will head on the road for a series against the Minnesota Twins.

Brewers Snap Three-Game Losing Streak

Brice Turang has 42 hits with 3 home runs, 16 RBIs, and 9 stolen bases, while Jackson Chourio has 45 hits with a team-high 13 doubles, 7 home runs, and 25 RBIs, and Sal Frelick has 36 hits as well as 2 triples and 7 stolen bases so far this season. Christian Yelich also has 8 stolen bases with 7 homers and 26 RBIs while also adding 3 doubles. Yelich also has a team-high 45 strikeouts up to this point in the year. William Contreras has 4 homers and 21 RBIs as well this season.

Why the Milwaukee Brewers will win

Milwaukee Brewers Player Prop Facts

Cleveland Guardians Recap

The Cleveland Guardians come into this game looking to rebound from the 3-0 loss they suffered at the hands of the Philadelphia Phillies in Sunday’s rubber match to drop to 23-17 on the year. After this series, the Guardians will head on the road for an interleague series against the Cincinnati Reds.

Guardians Drop Back-To-Back Games

Steven Kwan leads the Guardians with 52 hits as part of a .331 batting average and 4 home runs, 8 doubles, and 17 RBIs. Kyle Manzardo has 25 hits with 3 doubles, a triple, 9 home runs, and a team-high 22 RBIs as well this year. Gabriel Arias has a team-high 7 doubles but also 35 strikeouts, and Manzardo has a team-high 38 strikeouts so far this season. Arias has also added 4 home runs and 16 RBIs, and Jose Ramirez has chipped in 6 home runs and 18 RBIs.

Why the Cleveland Guardians will win

Cleveland Guardians Player Prop Facts

Total Runs Facts

Milwaukee Brewers vs. Cleveland Guardians Prediction

I’m leaning towards the Brewers here. The Guardians were on quite a roll before those losses to Philadelphia to close out the series, and now have arguably their weakest arm in Ben Lively going against the staff ace of the Brewers, and the Brewers, for my money, have just been playing the better baseball over the weekend. I think the edge in starting pitching is too much for Cleveland to overcome, even at home. Give me the Guardians.

Chris Ruffolo's Pick: Milwaukee Brewers -135

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