Milwaukee Brewers vs Cincinnati Reds Prediction 9/5/2026 Today’s MLB Picks

Nikos Lagouretos

2 hours ago

Aug 6, 2026; Cincinnati, Ohio, USA; Cincinnati Reds pitcher Andrew Abbott throws against the Athletics in the first inning at Great American Ball Park. Mandatory Credit: Aaron Doster-Imagn Images

MATCHUP	Milwaukee Brewers	Cincinnati Reds
Team Records	88-54	67-74
Spread	-1.5 -105	+1.5 -115
Moneyline	-167	+138
Total	Over 9 (-123)	Under 9 (102)
Where	Great American Ball Park, Cincinnati, Ohio
When	Saturday, September 5, 2026
Time	06:40 PM EDT
TV	MLB.TV

In this article, we will formulate a Brewers vs Reds Prediction for this MLB matchup on Saturday, September 5th in the second game of this series. Let’s take a look at the prediction for this MLB matchup.

Cincinnati Reds Preview

The Cincinnati Reds have a 67-74 record this season and are sitting in the 5th place of the NL Central. They have a 34-38 home record and are coming off a 7-10 home loss against the Brewers. They will face the Dodgers and the Brewers next.

The Cincinnati Reds have a .229 batting average this season, .308 OBP, and .396 slugging percentage. Cincinnati’s pitching staff has a 4.68 ERA and 1.43 WHIP. Elly De La Cruz is the Reds’ best hitter with a .276 batting average. Sal Stewart leads the team in RBI with 106, adding a team-high 31 home runs.

Andrew Abbott (L) is the projected starting pitcher for the Reds, with a 6-10 record, 4.49 ERA, and 1.44 WHIP.

Milwaukee Brewers Preview

The Milwaukee Brewers have an 88-54 record this season and are sitting in the 1st place of the NL Central. They have a 41-29 road record and are coming off a 10-7 road win against the Reds. They will face the Cubs and the Reds next.

The Milwaukee Brewers have a .257 batting average this season, .339 OBP, and .400 slugging percentage. Milwaukee’s pitching staff has a 3.50 ERA and 1.17 WHIP. Jackson Chourio is the Brewers’ best hitter with a .284 batting average. Brice Turang leads the team in RBI with 82, while Jake Bauers adds a team-high 23 home runs.

Dustin May (R) is the projected starting pitcher for the Brewers, with a 6-9 record, 4.69 ERA, and 1.32 WHIP.

Milwaukee Brewers @ Cincinnati Reds Betting Trends: September 5, 2026

Probable Starting Pitcher: Andrew Abbott Record this season: 6-10 ERA: 4.49
Home Record: 3-5
Last 5 against Brewers: 1-2

Why the Cincinnati Reds will win

The Reds have won each of their last seven night games at Great American Ball Park following a loss.
The Brewers have lost four of their last six games as road favorites against NL opponents following a win.
The Reds have covered the run line in each of their last six games as home underdogs against the Brewers following a loss.
The Brewers have failed to cover the run line in each of their last six games as favorites against the Reds following a road win.
The Brewers have trailed after 3 innings in each of their last four games as favorites.
The Reds have won the first inning in four of their last five games against the Brewers.

Probable Starting Pitcher: Dustin May Record this season: 6-9 ERA: 4.69
Road Record: 2-4
Last 5 against Reds: 0-0

Why the Milwaukee Brewers will win

The Brewers have won each of their last 11 Saturday night road games against NL Central opponents.
The Reds have lost each of their last six night games against the Brewers following a loss.
The Brewers have covered the run line each of their last five night games against teams that held a losing record.
The Reds have failed to cover the run line in eight of their last nine Saturday games.
The Reds have trailed after 3 innings in four of their last five games against NL Central opponents.
The Reds have trailed after 5 innings in each of their last six home games against NL Central opponents.
The Brewers have won the first inning in four of their last five games against opponents that held a losing record.

Total Runs Facts

Each of the Reds’ last six games against NL Central opponents have gone OVER the total runs line.
Seven of the Brewers’ last eight road games after playing the previous day have gone OVER the total runs line.
There has been at least one run scored in the first inning in seven of the Brewers’ last eight games as favorites.
There has been at least one run scored in the first inning in seven of the Reds’ last eight games as underdogs against NL Central opponents.

Cincinnati Reds Player Prop Facts

Sal Stewart has hit a home run in three of the Reds’ last four games against NL Central opponents.
Andrew Abbott has recorded four or more strikeouts in 29 of his last 34 appearances in night games.
Sal Stewart has recorded at least one hit in each of the Reds’ last 22 games against NL Central opponents that held a winning record.
Sal Stewart ranks 10th in the league in Home Runs (31) this season.

Milwaukee Brewers Player Prop Facts

Cooper Pratt has recorded at least one hit in each of his last 12 road appearances.
Bo Naylor has hit a home run in three of his last five appearances with his team as a road favorite against NL Central opponents.
Jake Bauers ranks 4th amongst qualified players for On Base Percentage (.391) this season.

Matchup/League Facts

The Reds rank 30th in the league for hits this season (1072).
The Reds rank 30th in the league for batting average this season (.229).
The Brewers rank 1st in the league for hits this season (1238).
The Brewers rank 30th in the league for home runs this season (131).

Brewers vs Reds Prediction

The Brewers are 8-2 in their last 10 meetings against the Reds and have won their last four visits in Cincinnati.

In this Brewers vs Reds Prediction, the Brewers are coming as -155 road favorites. I don’t like the pitching in this matchup as both starters have a combined 9.18 ERA and their home/away splits are even worse, as May has a 5.55 road ERA and Abbott a 4.78 home ERA. The opening game of this series had 17 total runs and both teams are 13-4 to the over in their last 17 games combined. Take the over 9.5 runs again today.