Milwaukee Brewers vs Chicago Cubs Prediction 10/8/2025 Today’s MLB Picks

In this article, we will formulate a Brewers vs Cubs Prediction for this MLB game on Wednesday, October 8th at the Wrigley Field in Game 3 of this NLDS series, with the Brewers having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs have a 94-73 record this season and were placed second in the NL Central. The Cubs have 52-32 home record and are 76-78 in over/under. They are coming off a 3-7 road defeat by the Brewers, and are 1-3 in their last 4 games. Under is 4-2 in their last 6 games.

The Cubs have a .249 batting average this season, .320 OBP and .430 Slugging percentage. Chicago’s pitching staff has a 3.79 ERA and 1.18 WHIP. Nico Hoerner leads the team with 7 hits, and he is the team’s best hitter, with a .368 batting average. Seiya Suzuki adds a team-high 4 RBI, while Michael Busch adds a team-high two home runs.

Jameson Taillon (R) is the projected starting pitcher for the Cubs, and he has a 0-0 record, 0.00 ERA and 0.50 WHIP in the postseason.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 99-65 record this season and were placed first in the NL Central. The Brewers have a 45-36 road record and are 79-80 in over/under. They are coming off a 7-3 home victory over the Cubs in Game 2, and have three consecutive wins. Over is 3-1 in their last 4 games.  

The Brewers have a .258 batting average this season, .332 OBP and .403 slugging percentage. Milwaukee’s pitching staff has a 3.58 ERA and 1.23 WHIP. Jackson Chourio leads the Brewers with 5 hits in the playoffs, adding a team-high 6 RBI. Blake He is also the team’s best hitter, with a .714 batting average, while William Contreras adds one home run.

Quinn Priester (R) is the projected starting pitcher for the Brewers, and he has a 13-3 record, 3.32 ERA and 1.24 WHIP.

Milwaukee Brewers @ the Chicago Cubs Betting Trends: October 8, 2025

• Probable Starting Pitcher: Jameson Taillon      Record this season (inc. playoffs): 11-7      ERA: 3.57
• Home Record: 5-2
• Last 5 against Brewers: 2-3

Why the Chicago Cubs will win

• The favorites have won each of the Cubs’ last 10 games.
• The Brewers have lost each of their last seven road playoff games.
• The favorites have covered the run line in each of the Cubs’ last 10 games.
• The Brewers have failed to cover the run line in eight of their last nine road games.
• The Cubs have led after 5 innings in each of their last six games as favorites.
• The Cubs have led after 3 innings in each of their last five Wednesday games against NL Central opponents that held a winning record.

• Probable Starting Pitcher: Quinn Priester      Record this season: 13-3      ERA: 3.32
• Road Record: 6-1
• Last 5 against Cubs: 1-0

Why the Milwaukee Brewers will win

• The Brewers have won each of their last five games as underdogs.
• The Cubs have lost each of their last six games against NL Central opponents that held a winning record.
• The Brewers have covered the run line in 26 of their last 27 games as underdogs.
• The Cubs have failed to cover the run line in seven of their last eight playoff games after not playing the previous day.
• The Cubs have trailed after 3 innings in each of their last four games against NL Central opponents that held a winning record.
• The Cubs have trailed after 5 innings in each of their last four games against NL Central opponents that held a winning record.

Total Runs Facts

• Each of the Cubs’ last seven playoff games as home favorites have gone UNDER the total runs line.
• Each of the Brewers’ last four playoff games against NL Central opponents have gone OVER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 14 of the Brewers’ last 16 games as road underdogs.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Cubs’ last five games against NL Central opponents.

Chicago Cubs Player Prop Facts

• Seiya Suzuki has hit a home run in four of the Cubs’ last five games as favorites.
• Seiya Suzuki has recorded at least one hit in each of his last 12 home appearances.
• Nico Hoerner ranks 6th in the league in Hits (178) this season.

Milwaukee Brewers Player Prop Facts

• Brice Turang has recorded at least one Double in each of his last three road appearances after not playing the previous day.
• Jackson Chourio has recorded at least one hit in each of his last 10 appearances with the Brewers as road underdogs.
• Danny Jansen has hit a home run in three of his last four appearances in day games.

Matchup/League Facts

• The Cubs rank 1st in the league for walks allowed this season (405).
• The Cubs rank T3rd in the league for RBIs this season (771).
• The Brewers rank 2nd in the league for on-base percentage this season (.332).
• The Brewers rank 2nd in the league for steals this season (164).

Brewers vs Cubs Prediction

The Brewers have won their last three meetings against the Cubs, but the Cubs are 3-1 in their last 4 meetings in Chicago. Over is 3-1 in their last 4 meetings.

In this Brewers vs Cubs Prediction, the Cubs are coming as -120 home favorites. The Cubs are with their backs against the wall, after losing both games in Milwaukee with a combined 16-6 score. Taillon takes the mound for Chicago, and he has been better at home with a 3.05 ERA, and in excellent form, having just two earned runs across his last four starts. Priester takes the mound for the Brewers, and he has at least two earned runs in his last four starts. I trust the red-hot Taillon to lead his team to a much-needed win and force a Game 4, so take the Cubs on the moneyline at home in this one.