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Milwaukee Brewers vs Chicago Cubs Prediction 10/8/2025 Today’s MLB Picks

Aug 19, 2025; Chicago, Illinois, USA;  Chicago Cubs pitcher Jameson Taillon (50) delivers during the first inning against the Milwaukee Brewers at Wrigley Field. Mandatory Credit: Matt Marton-Imagn Images

Aug 19, 2025; Chicago, Illinois, USA; Chicago Cubs pitcher Jameson Taillon (50) delivers during the first inning against the Milwaukee Brewers at Wrigley Field. Mandatory Credit: Matt Marton-Imagn Images

MATCHUP Milwaukee Brewers Chicago Cubs
Team Records 97-65 92-70
Where Wrigley Field, Chicago, Illinois
When Wednesday, October 8, 2025
Time 05:08 PM EDT
TV TBS

In this article, we will formulate a Brewers vs Cubs Prediction for this MLB game on Wednesday, October 8th at the Wrigley Field in Game 3 of this NLDS series, with the Brewers having the 2-0 lead. Let’s take a look at the prediction for this MLB matchup.

Chicago Cubs Preview

The Chicago Cubs have a 94-73 record this season and were placed second in the NL Central. The Cubs have 52-32 home record and are 76-78 in over/under. They are coming off a 3-7 road defeat by the Brewers, and are 1-3 in their last 4 games. Under is 4-2 in their last 6 games.

The Cubs have a .249 batting average this season, .320 OBP and .430 Slugging percentage. Chicago’s pitching staff has a 3.79 ERA and 1.18 WHIP. Nico Hoerner leads the team with 7 hits, and he is the team’s best hitter, with a .368 batting average. Seiya Suzuki adds a team-high 4 RBI, while Michael Busch adds a team-high two home runs.

Jameson Taillon (R) is the projected starting pitcher for the Cubs, and he has a 0-0 record, 0.00 ERA and 0.50 WHIP in the postseason.

Milwaukee Brewers Preview

The Milwaukee Brewers have a 99-65 record this season and were placed first in the NL Central. The Brewers have a 45-36 road record and are 79-80 in over/under. They are coming off a 7-3 home victory over the Cubs in Game 2, and have three consecutive wins. Over is 3-1 in their last 4 games.  

The Brewers have a .258 batting average this season, .332 OBP and .403 slugging percentage. Milwaukee’s pitching staff has a 3.58 ERA and 1.23 WHIP. Jackson Chourio leads the Brewers with 5 hits in the playoffs, adding a team-high 6 RBI. Blake He is also the team’s best hitter, with a .714 batting average, while William Contreras adds one home run.

Quinn Priester (R) is the projected starting pitcher for the Brewers, and he has a 13-3 record, 3.32 ERA and 1.24 WHIP.

Milwaukee Brewers @ the Chicago Cubs Betting Trends: October 8, 2025

Why the Chicago Cubs will win

Why the Milwaukee Brewers will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Milwaukee Brewers Player Prop Facts

Matchup/League Facts

Brewers vs Cubs Prediction

The Brewers have won their last three meetings against the Cubs, but the Cubs are 3-1 in their last 4 meetings in Chicago. Over is 3-1 in their last 4 meetings.

In this Brewers vs Cubs Prediction, the Cubs are coming as -120 home favorites. The Cubs are with their backs against the wall, after losing both games in Milwaukee with a combined 16-6 score. Taillon takes the mound for Chicago, and he has been better at home with a 3.05 ERA, and in excellent form, having just two earned runs across his last four starts. Priester takes the mound for the Brewers, and he has at least two earned runs in his last four starts. I trust the red-hot Taillon to lead his team to a much-needed win and force a Game 4, so take the Cubs on the moneyline at home in this one.

Nikos Lagouretos's Pick: Chicago Cubs -120

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