Mets vs White Sox Prediction 8/21/2026 Today’s MLB Picks

In this article we will formulate a Mets vs White Sox prediction for this MLB game on Friday, August 21st at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

New York Mets Betting Preview

The New York Mets are 58-70 this season after they won two out of three against the Padres by scores of 2-1, 2-5, and 4-2. In game three, New York had their lead cut to 2-1 in the fifth inning, but they scored two runs in the eighth to seal the win. The Mets recorded seven hits in the game and they were led by Benge, who went 2-4 with one home run and two RBIs. Stock allowed two hits and one earned run over 4.1 innings, while Lavender picked up the win and Senga got the save. Prior to that series, New York swept the Nationals in three games, but lost two out of three against the Braves before that. 

This season, New York has a 4.06 ERA with a 1.30 WHIP and a .237 opponent batting average, while they have scored 531 runs with a .235 batting average and a .307 on base percentage. Juan Soto (IL) has led the Mets with 21 home runs and 52 RBIs, while Bo Bichette has added 12 home runs and 64 RBIs. The projected starting pitcher for New York is Sean Manaea, who is 4-5 with a 4.22 ERA and a 1.32 WHIP over 111.0 innings pitched this season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 66-61 this year after they lost a makeup game with the Braves by a score of 2-0 on Thursday. Chicago allowed one run in the third inning and another in the seventh in the low scoring loss. The White Sox recorded one hit and they committed one error in the game, while they were led by Benintendi, who went 1-4. Kay allowed five hits and two earned runs over 6.0 innings for the loss, while Smith threw 1.1 innings in relief. Prior to that makeup game, Chicago lost two out of three against the Cubs, but did sweep the Tigers before that. 

This season, Chicago has a 4.06 ERA with a 1.29 WHIP and a .238 opponent batting average, while they have scored 605 runs with a .238 batting average and a .318 on base percentage. Colson Montgomery has led the White Sox with 26 home runs and 71 RBIs, while Miguel Vargas has added 28 home runs and 72 RBIs. The projected starting pitcher for Chicago is Sean Burke, who is 7-6 with a 3.15 ERA and a 1.11 WHIP over 140.0 innings pitched this year. 

Why the Chicago White Sox will win

• The White Sox have won each of their last five night games against National League opponents following a home loss.
• The Mets have lost four of their last five night games against American League opponents following a win.
• The favorites have covered the run line in each of the Mets’ last six games at Rate Field.
• The Mets have failed to cover the run line in each of their last five games following a home win.
• The Mets have trailed after 3 innings in three of their last four night games.
• The Mets have trailed after 5 innings in three of their last four games as underdogs.

Why the New York Mets will win

• The Mets have won each of their last seven games at Rate Field.
• The White Sox have lost each of their last six home games against the Mets following a loss.
• The Mets have covered the run line in each of their last six games as underdogs against AL Central opponents.
• The White Sox have failed to cover the run line in each of their last six night games against the Mets following a loss.
• The White Sox have trailed after 3 innings in three of their last four night games against NL East opponents.
• The White Sox have trailed after 5 innings in three of their last four games against NL East opponents.

Total Runs Facts

• Each of the Mets’ last four road games against American League opponents have gone OVER the total runs line.
• Four of the White Sox’s last five games as favorites against National League opponents have gone OVER the total runs line.
• There has been no run scored during the first inning in seven of the White Sox’s last eight games as home favorites against NL East opponents.
• There has been no run scored during the first inning in six of the Mets’ last seven games as road underdogs against AL Central opponents.

Chicago White Sox Player Prop Facts

• Munetaka Murakami has hit a home run in three of the White Sox’s last five night games against opponents that held a losing record.
• Sean Burke has recorded eight or more strikeouts in each of his last three appearances with the White Sox as favorites.
• Brenton Doyle has recorded at least one hit in each of his last seven appearances with his team as a home favorite against NL opponents.

New York Mets Player Prop Facts

• Sean Manaea has recorded seven or more strikeouts in four of his last five appearances with his team as an underdog against AL Central opponents.
• Bo Bichette has recorded at least one hit in each of his last 12 appearances at Rate Field.
• Sean Manaea has recorded a win in three of his four previous appearances against the White Sox.
• Luis Torrens has hit a home run in each of his last three road appearances against AL opponents.

Matchup/League Facts

• The White Sox rank 8th in the league for runs scored this season (605).
• The White Sox rank 23rd in the league for triples this season (12).
• The Mets rank 26th in the league for batting average this season (.235).
• The Mets rank 25th in the league for slugging percentage this season (.388).

Mets vs White Sox Prediction 

New York comes into this matchup after winning four of their last five games and they have allowed three runs or fewer in three of their last four. The Mets are 28-35 on the road this year, while the White Sox are 37-25 at home. Chicago has lost three of their last four games and they have scored three or fewer in three straight. The White Sox are starting Burke, who has allowed two earned runs or fewer in four of his last five starts, while Manaea has allowed two earned runs or fewer in four of his last five. Take the under here.

David Racey's Pick: Under 8