| MATCHUP | Los Angeles Dodgers | San Francisco Giants |
|---|---|---|
| Team Records | 16-7 | 10-13 |
| Spread | -1.5 -126 | +1.5 104 |
| Moneyline | -219 | +179 |
| Total | Over 7.5 (-118) | Under 7.5 (-102) |
| Where | Oracle Park, San Francisco, California | |
| When | Wednesday, April 22, 2026 | |
| Time | 09:45 PM EDT | |
| TV | MLB.TV | |
Los Angeles Dodgers Betting Preview
The Los Angeles Dodgers are 16-7 on the year and play the Marlins and Cubs next. The Los Angeles Dodgers are batting .286 on the season and have a .362 OBP, and a .494 slugging percentage. The Los Angeles Dodgers pitching staff has a 3.41 ERA and a 1.12 WHIP. Andy Pages leads the Los Angeles Dodgers with 30 hits and 21 RBI, while Freddie Freeman and Max Muncy have combined for 47 hits and 23 RBI.
Shohei Ohtani gets the ball for the Los Angeles Dodgers, and he is 2-0 with a 0.50 ERA and 18 strikeouts this season. Ohtani is 1-0 with a 0.60 ERA and 18 strikeouts in his career against the San Francisco Giants.
San Francisco Giants Betting Preview
The San Francisco Giants are 10-13 on the year and play the Marlins and Phillies next. The San Francisco Giants are batting. 250 on the season, have a .293 OBP, and have a .360 slugging percentage. The San Francisco Giants pitching staff has a 4.01 ERA and a 1.31 WHIP. Matt Chapman leads the San Francisco Giants with 26 hits and 12 RBI while Willy Adames and Luis Arraez have combined for 49 hits and 12 RBI.
Tyler Mahle gets the ball for the San Francisco Giants, and he is 0-3 with a 7.23 ERA and 21 strikeouts this season. Mahle is 2-3 with a 3.72 ERA and 28 strikeouts in his career against the Los Angeles Dodgers.
Why the San Francisco Giants will win
- The Giants have won four of their last five games as underdogs against National League opponents.
- The Dodgers have lost three of their last four games as favorites.
- The Dodgers have failed to cover the run line in each of their last seven Wednesday games as road favorites.
- The Giants have covered the run line in each of their last four night games against NL West opponents.
- The Dodgers have lost the first inning in each of their last three games at Oracle Park against NL West opponents that held a losing record.
- The Dodgers have trailed after 5 innings in three of their last four night games at Oracle Park against National League opponents.
- The Dodgers have trailed after 3 innings in four of their last five games at Oracle Park against NL West opponents that held a losing record.
Why the Los Angeles Dodgers will win
- The Giants have lost each of their last nine home games against the Dodgers following a win.
- The Dodgers have won each of their last nine games as favorites against the Giants following a loss.
- The Dodgers have covered the run line in each of their last 10 night games against the Giants at Oracle Park following a loss.
- The Giants have failed to cover the run line in each of their last seven night games against the Dodgers at Oracle Park following a home win.
Total Runs Facts
- Each of the Giants’ last five games as underdogs against National League opponents has gone UNDER the total runs line.
- Six of the Dodgers’ last eight night games against National League opponents have gone UNDER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in seven of the Dodgers’ last eight night games against National League opponents.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Giants’ last four home games against NL West opponents.
San Francisco Giants Player Prop Facts
- Rafael Devers has hit a home run in three of the Giants’ last seven games as home underdogs against NL opponents.
- Tyler Mahle has recorded five or more strikeouts in 20 of his last 25 home appearances against NL opponents.
- Luis Arraez has recorded at least one hit in each of his last 11 appearances in night games against NL teams that held a winning record.
Los Angeles Dodgers Player Prop Facts
- Shohei Ohtani has recorded eight or more strikeouts in each of his last three appearances with the Dodgers as favorites against NL opponents.
- Freddie Freeman has recorded at least one hit in 16 of his last 17 road appearances after playing the previous day.
- Mookie Betts has hit a home run in four of his last six appearances in night games against NL West teams that held a losing record.
- Andy Pages ranks T3rd in the league in Hits (30) this season.
Matchup/League Facts
- The Giants rank 29th in the league for runs scored this season (78).
- The Giants rank T29th in the league for home runs this season (13).
- The Dodgers rank 1st in the league for slugging percentage this season (.494).
- The Dodgers rank 1st in the league for on-base percentage this season (.362).
Los Angeles Dodgers vs San Francisco Giants Prediction
This was the week to fade the Dodgers and they’re starting to give back some of that profit. I said that the Dodgers would be losers on the season; just be patient. With that said, don’t expect the Dodgers to keep piling up losses in patches. The offense should break through against Mahle, who has been a disaster this season, and Ohtani has looked great on the mound. I’m surprised this line isn’t closer toward the -300 range. Either way, I’m going to side with the Dodgers, and I’ll lay the RL to shave down the price.