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Los Angeles Angels vs Houston Astros Prediction 3/27/2026 Today’s MLB Picks

Feb 11, 2026; Tempe, AZ, USA;  Los Angeles Angels Yusei Kikuchi during pitchers and catchers workouts at Tempe Diablo Stadium in Tempe, Arizona. Mandatory Credit: Arianna Grainey-Imagn Images

Feb 11, 2026; Tempe, AZ, USA; Los Angeles Angels Yusei Kikuchi during pitchers and catchers workouts at Tempe Diablo Stadium in Tempe, Arizona. Mandatory Credit: Arianna Grainey-Imagn Images

MATCHUP Los Angeles Angels Houston Astros
Team Records 1-0 0-1
Spread +1.5 -156 -1.5 129
Moneyline +135 -163
Total Over 8.5 (-115) Under 8.5 (-105)
Where Daikin Park, Houston, Texas
When Friday, March 27, 2026
Time 08:10 PM EDT
TV Apple TV

In this article, we will formulate an Angels vs Astros Prediction for this MLB matchup on Friday, March 27th. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Preview

The Houston Astros have a 0-1 record this season and are sitting on the last place of the AL West. They are coming off a 0-3 home defeat by the Angels and their previous three games were a 3-2 home loss to the Cardinals, a 7-5 away win over the Mets, and a 7-4 home loss to the Marlins in spring training.

The Astros have a .100 batting average this season, .250 OBP and .167 Slugging percentage. Houston’s pitching staff has a 3.00 ERA and 1.67 WHIP. Joey Loperfido leads the Astros with 1 hit, and he is the team’s best hitter with a .500 batting average.

Mike Burrows (R) is the projected starting pitcher for the Astros, and last season he had a 2-4 record, 3.94 ERA and 1.24 WHIP. The Astros will face off against the Red Sox and Athletics next. 

Los Angeles Angels Preview

The Los Angeles Angels have a 1-0 record this season and are sitting on the first place of the AL West. They are coming off a 3-0 away win over the Astros and their previous three games were a 3-0 away win over the Dodgers, a 7-7 away tie with the Dodgers, and a 13-5 home loss to the Dodgers in spring training.

The Angels have a .250 batting average this season, .372 OBP and .417 Slugging percentage. Los Angeles’ pitching staff has a 0.00 ERA and 1.00 WHIP. Mike Trout leads the Angels with 1 hit, and Jo Adell is the team’s best hitter with a .667 batting average. Mike Trout also leads the team in RBI with 1, adding a team-high 1 home run.

Yusei Kikuchi (L) is the projected starting pitcher for the Angels, and last season he had a 7-11 record, 3.99 ERA and 1.42 WHIP.

Los Angeles Angels @ Houston Astros Betting Trends: March 27, 2026

Why the Houston Astros will win

Why the Los Angeles Angels will win

Total Runs Facts

Houston Astros Player Prop Facts

Los Angeles Angels Player Prop Facts

Matchup/League Facts

Angels vs Astros Prediction

Both teams are tied 5-5 in their last 10 meetings and the Angels are 3-1 in their last 4 visits in Houston. Under is 7-1 in their last 8 meetings.

In this Angels vs Astros Prediction, the Astros are coming as -160 home favorites. The Astros got embarrassed in opening day yesterday, as they got shut out at home by the Angels while having perhaps their best pitcher on the mound. They have another shot tonight against Kikuchi, who has been far weaker on the road last season with a 5.04 road ERA and was light up in his last three starts against the Astros, having given up 10 earned runs in just 6.6 innings pitched. The Astros also had a superior bullpen last season, so I expect them to bounce back today and win this one at home.

Nikos Lagouretos's Pick: Houston Astros ML

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