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Los Angeles Angels vs Chicago Cubs Prediction 4/1/2026 Today’s MLB Picks

Mar 31, 2026; Chicago, Illinois, USA; Los Angeles Angels center fielder Mike Trout (27) celebrates his team’s victory over the Chicago Cubs with shortstop Zach Neto (9) at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

Mar 31, 2026; Chicago, Illinois, USA; Los Angeles Angels center fielder Mike Trout (27) celebrates his team’s victory over the Chicago Cubs with shortstop Zach Neto (9) at Wrigley Field. Mandatory Credit: Patrick Gorski-Imagn Images

MATCHUP Los Angeles Angels Chicago Cubs
Team Records 3-3 2-3
Spread +1.5 -171 -1.5 141
Moneyline +139 -168
Total Over 6 (-115) Under 6 (-105)
Where Wrigley Field, Chicago, Illinois
When Wednesday, April 1, 2026
Time 02:20 PM EDT
TV MLB.TV

The Los Angeles Angels and Chicago Cubs meet Wednesday in MLB action at Wrigley Field. Here’s a Los Angeles Angels vs. Chicago Cubs Prediction. This article will include a Los Angeles Angels vs. Chicago Cubs Pick.

Los Angeles Angels Betting Preview

The Los Angeles Angels are 3-3 on the year and play the Mariners and Braves next. The Los Angeles Angels are batting .217 on the season, have a .346 OBP, and have a .399 slugging percentage. The Los Angeles Angels pitching staff has a 3.53 ERA and a 1.53 WHIP. Nolan Schanuel leads the Los Angeles Angels with 7 hits and 5 RBI, while Jo Adell and Oswald Peraza have combined for 12 hits and 3 RBI.

Yusei Kikuchi gets the ball for the Los Angeles Angels, and he is 0-0 with a 4.15 ERA and 3 strikeouts this season. This will be Kikuchi’s first career game against the Chicago Cubs.

Chicago Cubs Betting Preview

The Chicago Cubs are 2-3 on the year and play the Guardians and Rays next. The Chicago Cubs are batting .213 on the season, have a .316 OBP, and have a .350 slugging percentage. The Chicago Cubs pitching staff has a 4.00 ERA and a 1.18 WHIP. Pete Crow-Armstrong leads the Chicago Cubs with 5 hits and 2 RBI while Ian Happ and Nico Hoerner have combined for 8 hits and 7 RBI.

Matthew Boyd gets the ball for the Chicago Cubs, and he is 0-1 with a 14.73 ERA and 7 strikeouts this season. Boyd is 2-1 with a 2.41 ERA and 17 strikeouts in his career against the Los Angeles Angels.

Why the Chicago Cubs will win

Why the Los Angeles Angels will win

Total Runs Facts

Chicago Cubs Player Prop Facts

Los Angeles Angels Player Prop Facts

Matchup/League Facts

Los Angeles Angels vs Chicago Cubs Prediction

The Cubs are getting the benefit of the doubt here and they are the better team. I’ve based the Angels for years and don’t think highly of this team. However, Boyd was downright terrible in his season debut and it’s hard to follow that up and lay juice in this spot. Kikuchi was sharp against the Astros and while he’s been hittable throughout his career, he’s also had moments where he’s looked like a strong middle-of-the-rotation guy. Quick turnaround, I’ll take the Angels and the more favorable price.

Randy Chambers's Pick: Los Angeles Angels

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