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Houston Astros vs Seattle Mariners Prediction 4/13/2026 Today’s MLB Picks

Apr 12, 2026; Seattle, Washington, USA; Seattle Mariners left fielder Randy Arozarena (56) avoids a tag by Houston Astros catcher Yainer Diaz (21) to score a run during the sixth inning at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn Images

Apr 12, 2026; Seattle, Washington, USA; Seattle Mariners left fielder Randy Arozarena (56) avoids a tag by Houston Astros catcher Yainer Diaz (21) to score a run during the sixth inning at T-Mobile Park. Mandatory Credit: Steven Bisig-Imagn Images

MATCHUP Houston Astros Seattle Mariners
Team Records 6-10 7-9
Where T-Mobile Park, Seattle, Washington
When Monday, April 13, 2026
Time 04:10 PM EDT
TV MLB.TV

The Houston Astros and Seattle Mariners meet Monday in MLB action at T-Mobile Park. Here’s a Houston Astros vs. Seattle Mariners Prediction. This article will include a Houston Astros vs. Seattle Mariners Pick.

Houston Astros Betting Preview

The Houston Astros are 6-10 on the year and play the Rockies and Cardinals next. The Houston Astros are batting .275 on the season and have a .369 OBP, and a .454 slugging percentage. The Houston Astros pitching staff has a 6.49 ERA and a 1.70 WHIP. Jose Altuve leads the Houston Astros with 19 hits and 6 RBI, while Christian Walker and Yordan Alvarez have combined for 35 hits and 27 RBI.

Mike Burrows gets the ball for the Houston Astros, and he is 1-2 with a 5.63 ERA and 15 strikeouts this season. This will be Burrows’ second career game against the Seattle Mariners.

Seattle Mariners Betting Preview

The Seattle Mariners are 7-9 on the year and play the Rangers and Padres next. The Seattle Mariners are batting. 198 on the season, have a .312 OBP, and have a .324 slugging percentage. The Seattle Mariners pitching staff has a 3.01 ERA and a 1.04 WHIP. Randy Arozarena leads the Seattle Mariners with 16 hits and 7 RBI while Cole Young and Julio Rodriguez have combined for 26 hits and 14 RBI.

George Kirby gets the ball for the Seattle Mariners, and he is 1-2 with a 3.60 ERA and 16 strikeouts this season. Kirby is 4-1 with a 2.15 ERA and 48 strikeouts in his career against the Houston Astros.

Why the Seattle Mariners will win

Why the Houston Astros will win

Total Runs Facts

Seattle Mariners Player Prop Facts

Houston Astros Player Prop Facts

Matchup/League Facts

Houston Astros vs Seattle Mariners Prediction

As I said in previous write-ups, the Astros are a tough sell given their pitching situation. The Astros are horrendous right now and Burrows has played a role in the disaster. Burrows has a 5.63 ERA and 1.75 WHIP through 16 innings. The Mariners have used this series to find their bats and this talented lineup is hard to stop once they get going. I have little use for the Astros and these issues on the bump. Give me the Mariners at home with the quick turnaround.

Randy Chambers's Pick: Seattle Mariners

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