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Houston Astros vs Oakland Athletics Prediction 07/25/2025 Picks

Jul 24, 2025; Houston, Texas, USA;  Athletics third baseman Gio Urshela (13) is out on a stolen base attempt as Houston Astros second baseman Brice Matthews (28) applies a tag during the eighth inning at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

Jul 24, 2025; Houston, Texas, USA; Athletics third baseman Gio Urshela (13) is out on a stolen base attempt as Houston Astros second baseman Brice Matthews (28) applies a tag during the eighth inning at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

MATCHUP Oakland Athletics Houston Astros
Team Records 43-62 60-43
Where Daikin Park, Houston, Texas
When Friday, July 25, 2025
Time 08:10 PM EDT
TV MLB.TV

In this article, we will formulate an Athletics vs Houston Astros Prediction for this MLB game on Friday, July 25th at the Daikin Park in the second game of this series, with the Athletics having the 1-0 lead. Let’s take a look at the prediction for this MLB matchup.

Houston Astros Preview

The Houston Astros currently hold a 60-43 record this season, placing them at the top of the AL West. They have a solid 33-20 record at home and are 44-54 in terms of over/under. Recently, they faced a 2-5 loss at home against the Athletics, which ended their previous four-game winning streak. The under has hit in their last three games, and they are set to play against the Nationals and the Red Sox next.

This season, the Astros boast a .259 batting average, a .323 on-base percentage, and a .408 slugging percentage. Their pitching staff has an impressive 3.60 ERA and a 1.18 WHIP. Jose Altuve is leading the team with 107 hits and also tops the team in RBIs with 53. Meanwhile, Jeremy Pena is the best hitter with a .322 batting average, and Isaac Paredes leads the team in home runs with 19.

Ryan Gusto (R) is the projected starter for the Astros, and he has a 6-3 record, 4.46 ERA and 1.42 WHIP.

Athletics Preview

The Athletics currently hold a 43-62 record this season, placing them at the bottom of the AL West. They have a 23-31 record on the road and are 56-44 in terms of over/under. Recently, they celebrated a 5-2 road win against the Astros, which snapped their previous four-game losing streak. The over has hit 5-2 in their last 7 games, and they are set to face the Diamondbacks and the Mariners next.

This season, the Athletics have a batting average of .249, with a .314 OBP and a .419 slugging percentage. Their pitching staff has an ERA of 5.20 and a WHIP of 1.43. Jacob Wilson is leading the team with 114 hits and boasts the best batting average at .311. Tyler Soderstrom tops the team with 57 RBIs, while Brent Rooker leads the team in home runs, with 21.

Jeffrey Springs (L) is the projected starter for the Athletics, and he has an 8-7 record, 4.18 ERA and 1.22 WHIP.

Why the Houston Astros will win

Why the Athletics will win

Total Runs Facts

Matchup/League Facts

Athletics vs Houston Astros Prediction

Houston is 5-3 in their last 8 meetings against the A’s, and are 3-1 in their last 4 home meetings against the A’s. Over is 6-2-1 in their last 9 head-to-head meetings.

In this prediction for the Athletics vs Houston Astros game, the Astros are favored at -160 as the home team. Houston deserves this favoritism, given their superior overall record and their strong performance at home. The A’s are struggling with the second-worst bullpen in the league, while the Astros boast a more potent offense. They’re sending Gusto to the mound, who is facing the A’s for the second time this season; his first outing against them was solid, allowing just one earned run over 5 innings. Meanwhile, Springs for the A’s is coming off a rough start, making this an ideal opportunity for the Astros to bounce back. I recommend taking the Houston Astros to secure a win at home today.

Nikos Lagouretos's Pick: Houston Astros -160

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