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Houston Astros vs Milwaukee Brewers Prediction 5/5/25 MLB Picks

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Milwaukee Brewers (17-18) vs Houston Astros (17-16)

Game Info: Monday, May 5, 2025 at 7:40 pm (American Family Field)

The Line: Betting Odds: Milwaukee Brewers -115 / Houston Astros -105 — Over/Under: 8

(Get latest betting odds)

The Houston Astros and Milwaukee Brewers meet Monday in MLB action at American Family Field. Here’s a Houston Astros vs Milwaukee Brewers Prediction. This article will include a Houston Astros vs Milwaukee Brewers Pick.

Houston Astros Betting Preview

The Houston Astros are 17-16 on the year and play the Reds, Royals, and Rangers next. The Houston Astros are batting .243 on the season, have a .314 OBP, and a .370 slugging percentage. The Houston Astros’ pitching staff has a 3.34 ERA and a 1.13 WHIP. Jeremy Pena leads the Houston Astros with 35 hits and 12 RBI, while Jose Altuve and Isaac Paredes have combined for 64 hits and 28 RBI. 

Ronel Blanco gets the ball for the Houston Astros, and he is 2-2 with a 5.08 ERA and 26 strikeouts this season. This will be Blanco’s first career game against the Milwaukee Brewers.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers are 17-18 on the year and play the Rays, Guardians, and Twins next. The Milwaukee Brewers are batting .238 on the season, have a .316 OBP, and a .356 slugging percentage. The Milwaukee Brewers’ pitching staff has a 4.32 ERA and a 1.34 WHIP. Brice Turang leads the Milwaukee Brewers with 41 hits and 16 RBI, while Jackson Chourio and Sal Frelick have combined for 73 hits and 33 RBI.

Tobias Myers gets the ball for the Milwaukee Brewers, and he is 0-0 with a 5.14 ERA and 6 strikeouts this season. This will be Myers’ first career game against the Houston Astros.

Why the Milwaukee Brewers will win

Why the Houston Astros will win

Milwaukee Brewers Player Prop Facts

Houston Astros Player Prop Facts

Houston Astros vs Milwaukee Brewers Prediction

I’m siding with the over in this series opener. The Astros and Brewers are capable offensively, and this isn’t a great pitching matchup. Blanco is better than what he’s shown up to this point, but he’s still allowed 23 hits and 16 runs in 28.1 innings. In 6.2 road innings this season, Blanco has a 9.45 ERA and .345 allowed batting average. Myers has pitched just seven innings this season and has still allowed six hits and four runs while walking seven. I expect a high-scoring game with two respectable lineups taking advantage of two struggling pitchers. Give me the over.

Randy Chambers's Pick: Over 8

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