Houston (85-75) vs Los Angeles (72-88)
September 27, 2025 at 09:38 PM EDT
The Line: Betting Odds: Los Angeles 0.0001 — Over/Under: 0.0001
The Houston Astros and Los Angeles Angels meet Saturday in MLB action at Angel Stadium. Here’s a Houston Astros vs Los Angeles Angels Prediction. This article will include a Houston Astros vs Los Angeles Angels Pick.
The Houston Astros are 85-75 on the year after playing the Athletics. The Houston Astros are batting .250 on the season, have a .315 OBP, and a .396 slugging percentage. The Houston Astros pitching staff has a 3.89 ERA and a 1.23 WHIP. Jose Altuve leads the Houston Astros with 155 hits and 77 RBI while Jeremy Pena and Christian Walker have combined for 286 hits and 147 RBI.
The Houston Astros didn’t announce a starting pitcher at the time the article was published.
The Los Angeles Angels are 72-88 on the year after playing the Royals. The Los Angeles Angels are batting .226 on the season, have a .298 OBP, and a .399 slugging percentage. The Los Angeles Angels pitching staff has a 4.87 ERA and a 1.43 WHIP. Taylor Ward leads the Los Angeles Angels with 131 hits and 103 RBI while Zach Neto and Nolan Schanuel have combined for 258 hits and 115 RBI.
Caden Dana gets the ball for the Los Angeles Angels, and he is 0-3 with a 6.39 ERA and 28 strikeouts this season. This will be Dana’s second career game against the Houston Astros.
It’s hard to take the Astros seriously with the way they’re losing this week, but they’re still a veteran team that knows how to win this time of year. You’d think they can get the job done now to stay in the playoff race. The Angels haven’t won two straight games in 17 days, and Dana has allowed 18 hits and 13 earned runs in his last 19.1 innings. In 10.2 home innings, Dana has an 8.44 ERA and .286 allowed batting average. There are no excuses for the Astros. It’s win or go home. Give me the Astros.
Houston Astros Betting Preview
The Houston Astros are 85-75 on the year after playing the Athletics. The Houston Astros are batting .250 on the season, have a .315 OBP, and a .396 slugging percentage. The Houston Astros pitching staff has a 3.89 ERA and a 1.23 WHIP. Jose Altuve leads the Houston Astros with 155 hits and 77 RBI while Jeremy Pena and Christian Walker have combined for 286 hits and 147 RBI.
The Houston Astros didn’t announce a starting pitcher at the time the article was published.
Los Angeles Angels Betting Preview
The Los Angeles Angels are 72-88 on the year after playing the Royals. The Los Angeles Angels are batting .226 on the season, have a .298 OBP, and a .399 slugging percentage. The Los Angeles Angels pitching staff has a 4.87 ERA and a 1.43 WHIP. Taylor Ward leads the Los Angeles Angels with 131 hits and 103 RBI while Zach Neto and Nolan Schanuel have combined for 258 hits and 115 RBI.
Caden Dana gets the ball for the Los Angeles Angels, and he is 0-3 with a 6.39 ERA and 28 strikeouts this season. This will be Dana’s second career game against the Houston Astros.
Houston Astros @ Los Angeles Angels Betting Trends: September 27, 2025
- Probable Starting Pitcher: Caden Dana Record this season: 0-3 ERA: 6.39
- Home Record: 0-1
- Last 5 against Astros: 0-1
Why the Los Angeles Angels will win
- The Astros have lost each of their last six night games against American League opponents.
- The Angels have won four of their last five home games after playing the previous day.
- The Astros have failed to cover the run line in each of their last six night games against AL West opponents.
- The Angels have covered the run line in each of their last four home games against the Astros.
- Probable Starting Pitcher: AJ Blubaugh Record this season: 3-1 ERA: 1.93
- Road Record: 3-0
- Last 5 against Angels: 0-0
Why the Houston Astros will win
- The Angels have lost each of their last 11 home games against the Astros following a win.
- The Astros have won each of their last seven games against the Angels following a road loss.
- The Angels have failed to cover the run line in each of their last five night games against the Astros following a home win.
- The Astros have covered the run line in six of their last seven games following a road loss.
- The Astros have led after 5 innings in five of their last six night games at Angel Stadium of Anaheim against AL West opponents.
Total Runs Facts
- Four of the Astros’ last five road games against AL West opponents have gone UNDER the total runs line.
- Four of the Angels’ last five games after playing the previous day have gone UNDER the total runs line.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the last four night games between the Astros and Angels.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Astros’ last five games at Angel Stadium of Anaheim.
Los Angeles Angels Player Prop Facts
- Taylor Ward has hit a home run in three of his last four appearances in night games.
- Luis Rengifo has recorded at least one hit in each of his last 10 Saturday night appearances against teams that held a winning record.
Houston Astros Player Prop Facts
- Christian Walker has hit a home run in each of the Astros’ last two road games.
- Christian Walker has recorded at least one hit in each of the Astros’ last 10 road games against AL opponents that held a losing record.
Matchup/League Facts
- The Angels rank 30th in the league for walks allowed this season (615).
- The Angels rank 29th in the league for hits this season (1200).
- The Astros rank 26th in the league for walks this season (466).
- The Astros rank T25th in the league for steals this season (81).
Houston Astros vs Los Angeles Angels Prediction
It’s hard to take the Astros seriously with the way they’re losing this week, but they’re still a veteran team that knows how to win this time of year. You’d think they can get the job done now to stay in the playoff race. The Angels haven’t won two straight games in 17 days, and Dana has allowed 18 hits and 13 earned runs in his last 19.1 innings. In 10.2 home innings, Dana has an 8.44 ERA and .286 allowed batting average. There are no excuses for the Astros. It’s win or go home. Give me the Astros.