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Houston Astros vs Chicago White Sox Prediction 5/3/25 MLB Picks

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Chicago White Sox (9-23) vs Houston Astros (16-15)

Game Info: Saturday, May 3, 2025 at 2:10 pm (Rate Field)

The Line: Betting Odds: Chicago White Sox +210 / Houston Astros -258 — Over/Under: 8

(Get latest betting odds)

The Houston Astros and Chicago White Sox meet Saturday in MLB action at Rate Field. Here’s a Houston Astros vs Chicago White Sox Prediction. This article will include a Houston Astros vs Chicago White Sox Pick.

Houston Astros Betting Preview

The Houston Astros are 16-15 on the year and play the Brewers, Reds, and Royals next. The Houston Astros are batting .238 on the season, have a .310 OBP, and a .359 slugging percentage. The Houston Astros’ pitching staff has a 3.36 ERA and a 1.10 WHIP. Jose Altuve leads the Houston Astros with 33 hits and 14 RBI, while Jeremy Pena and Isaac Paredes have combined for 61 hits and 26 RBI. 

Hunter Brown gets the ball for the Houston Astros, and he is 4-1 with a 1.22 ERA and 40 strikeouts this season. Brown is 3-0 with a 2.41 ERA and 20 strikeouts in his career against the Chicago White Sox.

Chicago White Sox Betting Preview

The Chicago White Sox are 9-23 on the year and play the Royals, Marlins, and Reds next. The Chicago White Sox are batting .216 on the season, have a .294 OBP, and a .333 slugging percentage. The Chicago White Sox pitching staff has a 4.01 ERA and a 1.35 WHIP. Lenyn Sosa leads the Chicago White Sox with 29 hits and 8 RBI, while Miguel Vargas and Brooks Baldwin have combined for 46 hits and 26 RBI.

Davis Martin gets the ball for the Chicago White Sox, and he is 1-3 with a 3.24 ERA and 21 strikeouts this season. This will be Martin’s first career game against the Houston Astros.

Why the Chicago White Sox will win

Why the Houston Astros will win

Chicago White Sox Player Prop Facts

Houston Astros Player Prop Facts

Houston Astros vs Chicago White Sox Prediction

Give the White Sox credit as they’ve won two straight Ames and their offense has come to life. Add that to Martin pitching well, posting a 3.24 ERA and 1.32 WHIP on the season, and you can make a case for a third straight win. Still, as I’ve said time and time again over the last three years, I have no use for the White Sox and their constant losing. Two wins don’t move the needle much when you consider the White Sox have 245 losses since the 2023 season. The Astros are comfortably the better side, and Brown has allowed 20 hits and three runs in his last 31 innings. Brown had an ERA of 0.87 in the month of April. Absolutely, dealing, folks. Give me the Astros and the RL for max betting value.

Randy Chambers's Pick: Houston Astros -1.5

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