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Houston Astros vs Boston Red Sox Prediction 08/03/2025 Today’s MLB Picks

Jul 29, 2025; Houston, Texas, USA; Houston Astros designated hitter Jose Altuve (27) hits an RBI single during the sixth inning against the Washington Nationals at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

Jul 29, 2025; Houston, Texas, USA; Houston Astros designated hitter Jose Altuve (27) hits an RBI single during the sixth inning against the Washington Nationals at Daikin Park. Mandatory Credit: Troy Taormina-Imagn Images

MATCHUP Houston Astros Boston Red Sox
Team Records 62-50 62-51
Where Fenway Park, Boston, Massachusetts
When Sunday, August 3, 2025
Time 11:35 AM EDT
TV Roku

The Houston Astros and the Boston Red Sox meet Sunday in MLB action from Fenway Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Houston Astros vs. Boston Red Sox prediction.

Starting Pitching Matchup

The Houston Astros will send out Framber Valdez for the start here and Valdez is 11-4 with a 2.62 ERA and 141 strikeouts this season. In his career, Valdez is 3-0 with a 1.77 ERA and 23 strikeouts against Boston. Lucas Giolito will get the nod for the Red Sox here and is 7-2 with a 3.80 ERA and 77 strikeouts this season. In his last five starts against Houston, Giolito is 1-3 with a 7.07 ERA and 28 strikeouts.

Houston Astros Recap

The Houston Astros come into this game looking to rebound from a 7-3 loss at the hands of the Red Sox last time out to sit at 62-49 on the year. After this series, the Astros will head on the road for a series against the Marlins.

Astros Lose 7 Of Their Last 9

Jose Altuve has 114 hits including 17 doubles, 18 home runs and 57 RBIs. Jeremy Pena also has 102 hits with 18 doubles, 11 homers and 40 RBIs with 15 stolen bases as well. Jake Meyers has 15 doubles as well and Christian Walker has 13 home runs and 55 RBIs but has also accrued a team-high 116 strikeouts so far this season. Altuve also has 6 stolen bases while Jake Meyers has 14 stolen bases this season. Isaac Paredes also has a team-high 19 home runs with 50 RBIs of his own and Cam Smith has contributed 7 homers and 45 RBIs.

Houston Astros Player Prop Facts

Boston Red Sox Recap

The Boston Red Sox come into this game looking to build on their win over the Astros from Saturday’s matchup to improve to 61-51 this season. After this series, the Red Sox will duke it out with the Kansas City Royals at home.

Red Sox Win 4 In A Row & 6 Of Last 7

Alex Bregman has 73 hits including 20 doubles along with 14 home runs and 44 RBIs this season. Trevor Story’s added 102 hits with 17 home runs, 65 RBIs and 17 stolen bases while Jarren Duran has 116 hits with 29 doubles, 12 triples, 11 home runs, 60 RBIs and a team-high 18 stolen bases. Kristian Campbell’s added 51 hits with 10 doubles, 6 homers and 21 RBIs while Wilyer Abreu has 20 home runs with 57 RBIs and 6 stolen bases and Ceddanne Rafaela has 14 homers, 21 doubles, 2 triples, 49 RBIs and 14 stolen bases this season.

Why the Boston Red Sox will win

Boston Red Sox Player Prop Facts

Total Runs Facts

Houston Astros vs. Boston Red Sox Prediction

I’m going to side with the Astros here. I get the case to be made for the Red Sox who are in better form right now, but the Astros have a seismic edge in starting pitching here with Valdez going and Giolito’s been far less effective at home over the course of the season. I think Houston has to get it together at some point and I think they do here to salvage something from this series. Give me the Astros here.

Chris Ruffolo's Pick: Houston -125

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