Houston (84-74) vs Oakland (75-83)
September 25, 2025 at 03:35 PM EDT
The Line: Betting Odds: Oakland — Over/Under:
The Houston Astros and Athletics meet Thursday in MLB action at Sutter Health Park. Here’s a Houston Astros vs Athletics Prediction. This article will include a Houston Astros vs Athletics Pick.
The Houston Astros are 84-74 on the year and play the Angels next. The Houston Astros are batting .250 on the season, have a .315 OBP, and a .396 slugging percentage. The Houston Astros pitching staff has a 3.88 ERA and a 1.22 WHIP. Jose Altuve leads the Houston Astros with 153 hits and 75 RBI, while Jeremy Pena and Christian Walker have combined for 284 hits and 144 RBI.
Framber Valdez gets the ball for the Houston Astros, and he is 12-11 with a 3.75 ERA and 177 strikeouts this season. Valdez is 7-4 with a 2.66 ERA and 88 strikeouts in his career against the Athletics.
The Athletics are 75-83 on the year and play the Royals next. The Athletics are batting .253 on the season, have a .318 OBP, and a .432 slugging percentage. The Athletics pitching staff has a 4.66 ERA and a 1.36 WHIP. Brent Rooker leads the Athletics with 163 hits and 89 RBI while Tyler Soderstrom and Jacob Wilson have combined for 304 hits and 153 RBI.
J.T. Ginn gets the ball for the Athletics, and he is 4-6 with a 4.57 ERA and 95 strikeouts this season. Ginn is 1-0 with a 1.69 ERA and 9 strikeouts in his career against the Houston Astros.
The Astros looked like a team that was going to win the AL West to falling out of the wild card race. The Astros are in trouble. And while you’d think they could turn it around against the Athletics, Valdez has allowed 25 hits and 19 earned runs in his last 20.2 innings. In 90.2 road innings, Valdez has a 4.96 ERA and .254 allowed batting average. The Athletics are playing until the finish line, and Ginn has allowed 12 hits and 3 runs in his last 15.1 innings. I’m going to side with the Athletics, as the Astros picked the wrong week to play poorly.
Houston Astros Betting Preview
The Houston Astros are 84-74 on the year and play the Angels next. The Houston Astros are batting .250 on the season, have a .315 OBP, and a .396 slugging percentage. The Houston Astros pitching staff has a 3.88 ERA and a 1.22 WHIP. Jose Altuve leads the Houston Astros with 153 hits and 75 RBI, while Jeremy Pena and Christian Walker have combined for 284 hits and 144 RBI.
Framber Valdez gets the ball for the Houston Astros, and he is 12-11 with a 3.75 ERA and 177 strikeouts this season. Valdez is 7-4 with a 2.66 ERA and 88 strikeouts in his career against the Athletics.
Athletics Betting Preview
The Athletics are 75-83 on the year and play the Royals next. The Athletics are batting .253 on the season, have a .318 OBP, and a .432 slugging percentage. The Athletics pitching staff has a 4.66 ERA and a 1.36 WHIP. Brent Rooker leads the Athletics with 163 hits and 89 RBI while Tyler Soderstrom and Jacob Wilson have combined for 304 hits and 153 RBI.
J.T. Ginn gets the ball for the Athletics, and he is 4-6 with a 4.57 ERA and 95 strikeouts this season. Ginn is 1-0 with a 1.69 ERA and 9 strikeouts in his career against the Houston Astros.
Houston Astros @ Athletics Betting Trends: September 25, 2025
- Probable Starting Pitcher: J.T. Ginn Record this season: 4-6 ERA: 4.57
- Home Record: 1-4
- Last 5 against Astros: 1-0
Why the Athletics will win
- The Athletics have won each of their last six home games.
- The Astros have lost each of their last five games against AL West opponents.
- The Athletics have covered the run line in each of their last seven games against the Astros.
- The Astros have failed to cover the run line in 15 of their last 17 games against AL West opponents that held a losing record.
- The Athletics have led after 5 innings in each of their last four games against opponents that held a winning record.
- The Astros have trailed after 3 innings in four of their last five games against AL West opponents.
- Probable Starting Pitcher: Framber Valdez Record this season: 12-11 ERA: 3.75
- Road Record: 6-7
- Last 5 against Athletics: 3-1
Why the Houston Astros will win
- The Astros have won each of their last 12 Thursday day games against American League opponents that held a losing record.
- The Athletics have lost each of their last four day games against AL West opponents.
- The Astros have covered the run line in five of their last six games following a road loss.
- The Athletics have failed to cover the run line in each of their last three day games against AL West opponents following a win.
Total Runs Facts
- Eight of the Astros’ last nine road games against American League opponents have gone UNDER the total runs line.
- Each of the Athletics’ last five home games against American League opponents have gone UNDER the total runs line.
- The ‘Inning 1 OVER 0.5 runs’ market has hit in nine of the Athletics’ last 10 day games against AL West opponents.
- The ‘Inning 1 UNDER 0.5 runs’ market has hit in seven of the Astros’ last eight day games against AL West opponents.
Matchup/League Facts
- The Athletics are one of only four teams in the league to rank top 10 in both home runs and batting average this season.
- The Athletics rank 27th in the league for ERA this season (4.66).
- The Astros rank 26th in the league for triples this season (12).
- The Astros rank 26th in the league for walks this season (458).
Houston Astros vs Athletics Prediction
The Astros looked like a team that was going to win the AL West to falling out of the wild card race. The Astros are in trouble. And while you’d think they could turn it around against the Athletics, Valdez has allowed 25 hits and 19 earned runs in his last 20.2 innings. In 90.2 road innings, Valdez has a 4.96 ERA and .254 allowed batting average. The Athletics are playing until the finish line, and Ginn has allowed 12 hits and 3 runs in his last 15.1 innings. I’m going to side with the Athletics, as the Astros picked the wrong week to play poorly.