Guardians vs Yankees Prediction 6/5/25 MLB Picks

In this article, we will formulate a Guardians vs Yankees prediction for this MLB game on Thursday, June 5th at Yankee Stadium in New York. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 33-27 this year after they split the first two games in this series by scores of 2-3 and 4-0. In their game two win, Cleveland scored three runs in the first inning, and they were able to add an insurance run in the eighth to seal the win. The Guardians recorded 12 hits and they committed one error in the game, while they were led by Martinez, who went 1-5 with one home run and two RBIs in the win. Cleveland started Ortiz, who allowed three hits and zero earned runs over 5.2 innings for the win, while Herrin picked up a hold in relief. 

Prior to this series, the Guardians won two out of three against the Angels, but lost two out of three against the Dodgers before that. Cleveland has won three of their last four games, and they are currently second in the AL Central standings. The Cleveland pitching staff has a 3.98 ERA with a 1.37 WHIP and a .251 opponent batting average, while the offense has scored 241 runs with a .236 batting average and a .308 on-base percentage this season. Jose Ramirez has led Cleveland with 11 home runs and 29 RBIs, while Kyle Manzardo has also added 11 home runs and 29 RBIs this year. The projected starting pitcher for Cleveland is Slade Cecconi, who is 1-1 with a 5.28 ERA and a 1.43 WHIP over 15.1 innings pitched this year. 

New York Yankees Betting Preview

The New York Yankees are 37-23 this season after they lost game two by a score of 4-0 on Wednesday night. New York fell behind in the first inning, and their offense never showed up in the shutout loss. The Yankees recorded just five hits in the game, and they were led by Rice and Judge, who both had two hits in the loss. New York started Schmidt, who allowed seven hits and three earned runs over 5.2 innings for the loss, while Cruz allowed one earned run in relief. 

Prior to this series, the Yankees lost two out of three against the Dodgers, but did sweep the Angels in three games before that. New York has won seven of their last ten games, and they are currently first in the AL East standings. The New York pitching staff has a 3.58 ERA with a 1.19 WHIP and a .218 opponent batting average, while the offense has scored 322 runs with a .257 batting average and a .342 on-base percentage this season. Aaron Judge has led New York with 21 home runs and 50 RBIs, while Trent Grisham has added 13 home runs and 26 RBIs this year. The projected starting pitcher for New York is Max Fried, who is 7-1 with a 1.92 ERA and a 0.97 WHIP over 75.0 innings pitched this season. 

Why the Yankees will beat the Guardians 

• The Guardians have lost each of their last 10 night games against the Yankees at Yankee Stadium following a win.
• The Yankees have won seven of their last eight home games against AL Central opponents following a loss.
• The Guardians have failed to cover the run line in seven of their last eight road games against AL East opponents following a road win.
• The Yankees have covered the run line in each of their last five night games against American League opponents following a loss.
• The Yankees have led after 5 innings in five of their last six games against American League opponents.

Total Runs Facts

• Each of the Yankees’ last 10 games against American League opponents have gone UNDER the total runs line.
• Six of the Guardians’ last seven road games have gone UNDER the total runs line.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in 10 of the Yankees’ last 12 games at Yankee Stadium.
• The ‘Inning 1 UNDER 0.5 runs’ market has hit in four of the Guardians’ last five games.

New York Yankees Player Prop Facts

• Giancarlo Stanton has recorded at least one RBI in seven of his last eight appearances against AL Central opponents.
• Jazz Chisholm has scored at least one run in six of the Yankees’ last seven games as favorites against AL Central opponents.
• Cody Bellinger has recorded at least one hit in each of the Yankees’ last 10 home games against opponents that held a winning record.
• Max Fried has recorded six or more strikeouts in each of his six previous appearances with his team as a favorite against AL Central opponents.
• Max Fried has recorded a win in seven of his eight previous appearances against AL Central opponents.
• Giancarlo Stanton has hit a home run in four of his last five appearances with the Yankees as favorites against the Guardians.
• DJ LeMahieu has recorded at least one Single in 10 of his last 11 home appearances against the Guardians after playing the previous day.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has scored at least one run in 10 of the Guardians’ last 11 games as underdogs.
• Jose Ramirez has recorded at least one hit in each of his last 20 appearances with the Guardians as underdogs.
• Carlos Santana has hit a home run in 12 of his last 34 appearances with his team as a road underdog against AL opponents.
• Steven Kwan has recorded at least one Single in 11 of the Guardians’ last 12 night games against AL opponents that held a winning record.

Guardians vs Yankees Prediction 

Cleveland picked up the shutout win in game two of this series last night, and they have won three of their last four games. The Guardians are 16-16 on the road this year, while the Yankees are 19-10 at home. New York has been very good over the last few weeks, but their offense has started to cool off. The Yankees have scored three runs or fewer in three of their last four games, and they are facing Cecconi, who allowed seven hits and five earned runs in his last start. Cleveland has also been lower scoring in recent games, and they will go against Fried, who has been elite for most of the season, but did allow six earned runs last time out. I expect a bounce-back outing from Fried in this game, and I like the Yankees to win by at least two runs here.