Guardians vs White Sox Prediction 8/9/2025 Today’s MLB Picks

In this article we will formulate a Guardians vs White Sox prediction for this MLB game on Saturday, August 9th at Rate Field in Chicago, Illinois. Let’s take a look at the prediction for this MLB matchup. 

Cleveland Guardians Betting Preview

The Cleveland Guardians are 60-55 this season after they won game one by a score of 9-5 on Friday night. Cleveland jumped out to a 9-1 lead in the fourth inning and they put it on cruise control for the win. The Guardians recorded 10 hits and they committed one error in the game, while they were led by Santana, who went 2-4 with four RBIs in the win. Cleveland started Bibee, who allowed five hits and four earned runs over 5.1 innings for the win, while Junis allowed one earned run in relief. 

Prior to this series, the Guardians won all three games against the Mets and two out of three against the Twins. Cleveland has won eight of their last nine games and they are currently second in the AL Central standings. The Cleveland pitching staff has a 3.83 ERA with a 1.30 WHIP and a .240 opponent batting average, while the offense has scored 459 runs with a .229 batting average and a .301 on base percentage this season. Jose Ramirez has led Cleveland with 23 home runs and 61 RBIs, while Kyle Manzardo has added 18 home runs and 49 RBIs this year. The projected starting pitcher for Cleveland is Joey Cantillo, who is 2-2 with a 4.37 ERA and a 1.44 WHIP over 55.2 innings pitched this season. 

Chicago White Sox Betting Preview

The Chicago White Sox are 42-74 this year after they lost game one by a score of 9-5 on Friday. Chicago did score the last four runs in the game, but they never had a chance in the game one loss. The White Sox recorded nine hits in the game and they were led by Mead, who went 1-4 with two RBIs in the loss. Chicago started Civale, who allowed eight hits and nine earned runs over 3.1 innings for the loss, while Vasil and Gonzalez combined for 5.2 scoreless innings. 

Prior to this series, the White Sox lost all three against the Mariners, but did win two out of three against the Angels before that. Chicago has lost five games in a row and they are currently last in the AL Central standings. The Chicago pitching staff has a 4.17 ERA with a 1.37 WHIP and a .248 opponent batting average, while the offense has scored 445 runs with a .229 batting average and a .300 on base percentage this season. Miguel Vargas has led Chicago with 13 home runs and 44 RBIs, while Andrew Benintendi has added 14 home runs and 44 RBIs this year. The projected starting pitcher for Chicago is Sean Burke, who is 4-8 with a 4.23 ERA and a 1.41 WHIP over 110.2 innings pitched this year. 

Why the White Sox will beat the Guardians

• The underdogs have won four of the Guardians’ last five games.
• The White Sox have covered the run line in each of their last seven games as underdogs following a home loss.
• The Guardians have failed to cover the run line in six of their last seven games against American League opponents following a win.

Why the Guardians will beat the White Sox

• The Guardians have won each of their last six night games against American League opponents.
• The White Sox have lost 16 of their last 18 night games against AL Central opponents that held a winning record.
• The Guardians have covered the run line in each of their last four games.
• The White Sox have failed to cover the run line each of their last four night games against teams that held a winning record.
• The Guardians have led after 5 innings in each of their last five night games against American League opponents that held a losing record.
• The White Sox have trailed after 3 innings in each of their last three games against American League opponents that held a winning record.

Total Runs Facts

• Four of the White Sox’s last five games have gone OVER the total runs line.
• Each of the Guardians’ last three games against AL Central opponents have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Guardians’ last four night games against AL Central opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the White Sox’s last five games.

Chicago White Sox Player Prop Facts

• Luis Robert has recorded at least one hit in 13 of his last 14 appearances in night games.
• Michael A. Taylor has hit a home run in two of the White Sox’s last three games against opponents that held a winning record.

Cleveland Guardians Player Prop Facts

• Jose Ramirez has recorded at least one hit in each of the Guardians’ last 11 games against AL opponents.
• Jose Ramirez has hit a home run in two of the Guardians’ last three games against opponents that held a losing record.
• Jose Ramirez has recorded a Double in three of the Guardians’ last four night games against AL opponents that held a losing record.

Guardians vs White Sox Prediction 

Cleveland rolled into Chicago and picked up an easy win on Friday night, as they continue to play their best baseball of the season. The Guardians are 31-28 on the road this year, while the White Sox are 24-33 at home. Chicago has allowed at least eight runs in four of their last five games and they are starting Burke, who has allowed two earned runs or fewer in three of his last four starts. The Guardians are going with Cantillo, who has allowed 4, 3, 1, and 4 earned runs in his last four outings. Take the over here.